Results 111 to 120 of about 605,989 (306)
Lithuania: Fertility decline and its determinants [PDF]
Since the beginning of the 1990s, Lithuania has been undergoing significant transformations in family life and has experienced a precipitous decline in fertility.
Aiva Jasilioniene +1 more
core
Advanced Science, EarlyView.This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu +23 more
wiley +1 more source
Examining the predictive value of fertility preferences among Ghanaian women [PDF]
Despite extensive research, doubts remain regarding the degree of correspondence between prior stated fertility preferences and subsequent fertility behavior. Preference instability is a factor that potentially undermines predictiveness.
John Casterline +2 more
core
Advanced Science, EarlyView.The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng +8 more
wiley +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly
Advanced Science, EarlyView.LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang +6 more
wiley +1 more source
Colossal Magnetic‐Field‐Induced Anomalous Hall Conductivity in a Kagome Antiferromagnet YMn6Sn6
Advanced Science, EarlyView.Magnetic‐field‐driven spin canting in the kagome antiferromagnet YMn6Sn6${\rm YMn}_6{\rm Sn}_6$ reshapes flat and Dirac bands near the Fermi level, redistributing Berry curvature and producing colossal anomalous Hall conductivity. The study reveals how magnetic configuration and clean‐limit skew scattering cooperate to amplify Hall transport, offering ...
Minhyuk Choi +9 more
wiley +1 more source
Tempo-Adjusted Period Parity Progression Measures, Fertility Postponement and Completed Cohort Fertility [PDF]
In this paper we introduce a new set of tempo-adjusted period parity progression measures in order to account for two distinct implications caused by delays in childbearing: tempo distortions imply an underestimation of the quantum of fertility in ...
Hans-Peter Kohler, José Antonio Ortega
core
Advanced Science, EarlyView.scGEN combines attribute–structure encoding, adaptive hard‐sample weighting, and regularized zero‐inflated negative binomial loss to resolve ambiguous single‐cell states. In the developing human pituitary, refined annotations reveal Pre.Gonado cells at 7 weeks and previously obscured developmental communication networks.
Fang Huang +16 more
wiley +1 more source