Results 161 to 170 of about 1,482,535 (355)

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

open access: yesAdvanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li   +9 more
wiley   +1 more source

Testing the Inverseness of Fertility and Labor Supply: The Case of Ethiopia [PDF]

open access: yes
We test the inverseness of fertility and labor supply for married women in Ethiopia to determine if previous research (focusing on developed countries) that has found an inverse relationship between fertility and labor supply is applicable to least ...
Kimmel, Jean, Solomon, Blen
core  

Reproductive issues in the Torah [PDF]

open access: yes, 2015
Fertility was the basis of primitive man’s economy. It is therefore not surprising to find that various facets of fertility and reproduction are mentioned and commented upon in connection to religious based texts from the period.
Savona-Ventura, Charles
core  

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

open access: yesAdvanced Science, EarlyView.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park   +5 more
wiley   +1 more source

Immunosuppressive drugs and fertility [PDF]

open access: gold, 2015
Clara Leroy   +10 more
openalex   +1 more source

The end of 'lowest-low' fertility? (with supplementary materials) [PDF]

open access: yes
Period fertility rates fell to previously unseen low levels in a large number of countries beginning in the early 1990s. The persistence of Total Fertility Rates under 1.3 raised the possibility of dramatic, rapid population aging as well as population ...
Aiva Jasilioniene   +2 more
core  

U.S. Births Remain Low as the Great Recession Wanes; More Than Three Million Fewer Births and Still Counting [PDF]

open access: yes, 2016
In this fact sheet, author Ken Johnson discusses how since the onset of the Great Recession, there have been 3.4 million fewer U.S. births than expected. National Center for Health Statistics data for 2015 show the lowest general fertility rate on record
Johnson, Kenneth M.
core   +1 more source

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

open access: yesAdvanced Science, EarlyView.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun   +9 more
wiley   +1 more source

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