Results 81 to 90 of about 1,095,790 (363)

Genetic Deconvolution of Embryonic and Maternal Cell‐Free DNA in Spent Culture Medium of Human Preimplantation Embryo Through Deep Learning

open access: yesAdvanced Science, EarlyView.
DECENT is a deep learning method that enhances noninvasive preimplantation genetic testing by accurately reconstructing embryonic copy number variations (CNVs) from cell‐free DNA in spent embryo culture media. By mitigating maternal contamination, DECENT improves diagnostic accuracy, even with high contamination levels, offering a reliable, noninvasive
Zhenyi Zhang   +3 more
wiley   +1 more source

A comprehensive review of the impact of COVID-19 on human reproductive biology, assisted reproduction care and pregnancy: a Canadian perspective

open access: yesJournal of Ovarian Research, 2020
Currently, the world is in the seventh month of the COVID-19 pandemic. Globally, infections with novel SARS-CoV-2 virus are continuously rising with mounting numbers of deaths. International and local public health responses, almost in synchrony, imposed
Mitko Madjunkov   +2 more
doaj   +1 more source

Future Fertility in Low Fertility Countries [PDF]

open access: yes, 2014
Chapter 3 is the first of six that present a comprehensive science-based assessment of what we know today about the drivers of future fertility, mortality, migration, and education. This chapter concerns countries with currently low fertility. It presents and justifies assumptions for future fertility trajectories based on an overview of recent ...
1. M Jalal Abbasi-Shavazi   +15 more
openaire   +5 more sources

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

open access: yesAdvanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma   +18 more
wiley   +1 more source

Tempo-Adjusted Period Parity Progression Measures: [PDF]

open access: yes
In this paper we apply tempo-adjusted period parity progression ratios (Kohler and Ortega 2002) to Sweden, the Netherlands and Spain. These countries represent three distinct demographic patterns in contemporary Europe and are of particular interest for ...
Hans-Peter Kohler, José Antonio Ortega
core  

MYC Binding Near Transcriptional End Sites Regulates Basal Gene Expression, Read‐Through Transcription, and Intragenic Contacts

open access: yesAdvanced Science, EarlyView.
MYC is a transcription factor (TF) that binds DNA near transcriptional start sites (TSSs) and within enhancer elements. Here, unappreciated sites of MYC binding in the vicinity of transcriptional end sites (TESs) of many genes in multiple cell types in association with numerous other TFs are described previously.
Huabo Wang   +5 more
wiley   +1 more source

The Fertility Transition Around the World - 1950-2005 [PDF]

open access: yes
In this paper we analyze the distribution of fertility rates across the world using parametric mixture models. We demonstrate the existence of twin peaks and the division of the world's countries in two distinct components: a high-fertility regime and a ...
Strulik, Holger, Vollmer, Sebastian
core  

Effectiveness of Microdosing in Comparison to Broadcasting and Banding Vermicompost Application for Maize (Zea mays L.) Production in Smallholder Farming of Semiarid Tigray Region of Ethiopia

open access: yesInternational Journal of Agronomy
Optimizing organic fertilizer recommendations can be cost-effective and affordable for resource-poor farmers by increasing crop yield and income. This field experiment was conducted to determine the most effective vermicompost application method for ...
Kinfe Tekulu   +5 more
doaj   +1 more source

Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model

open access: yesAdvanced Science, EarlyView.
A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana   +10 more
wiley   +1 more source

Soil Fertility Protocol [PDF]

open access: yes, 2003
The purpose of this resource is to measure the amounts of nitrogen, phosphorous and potassium in each horizon in a soil profile. Using a NPK test kit, students mix a dry, sieved soil sample into a solution and chemically extract the N, P, and K as ...
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core  

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