Results 131 to 140 of about 17,836,783 (339)
Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective
Advanced Science, EarlyView.Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok +4 more
wiley +1 more source
The Future of American Fertility [PDF]
This paper reviews the major social and demographic forces influencing American fertility levels with the aim of predicting changes during the next three decades.
Caroline Sten Hartnett +1 more
core
MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis
Advanced Science, EarlyView.A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li +9 more
wiley +1 more source
A review of migration and fertility theory through the lens of African immigrant fertility in France [PDF]
This paper evaluates fertility and migration theory in order to further understand the impact of migration on fertility. I first analyze the fertility and migration literature separately and then look at the burgeoning literature on the impact of ...
Anne Genereux
core
Advanced Science, EarlyView.Correcting the apparent priming effect resolves systematic biases in Asian rice fertilizer nitrogen accounting. Net soil retention drops below 7%, while 48% of fertilizer escapes, inflicting US$98.53 billion in annual reactive‐nitrogen damages. High‐resolution mapping uncovers N‐risk archetypes across 42% of the rice area, delivering a spatially ...
Xiuyun Liu +5 more
wiley +1 more source
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Advanced Science, EarlyView.Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
The Effects of Conflict on Fertility in Rwanda [PDF]
The aim of this paper is to study the short and long-term fertility effects of mass violent conflict on different population sub-groups. The authors pool three nationally representative demographic and health surveys from before and after the genocide in
Kati Schindler, Tilman Brück
core +2 more sources
, 2011 Includes abstract.Includes bibliographical references (leaves 66-68).Apartheid policies have been criticised for widening inequalities between population groups in South Africa. They have also been considered to have dictated differentials in demographic
Chingwalu, Julius
core
Changing determinants of low fertility and diffusion: a spatial analysis for Italy
, 2014 Italy is a case study in lowest-low fertility. Its internal heterogeneity is substantial and changes over time. Historically, the South had higher fertility, but in recent years it the North has become the area with the highest fertility.
Billari, Francesco +4 more
core +1 more source
Advanced Science, EarlyView.eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu +12 more
wiley +1 more source