Results 101 to 110 of about 341,999 (308)

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

The Effects of Tillage and the Combined Application of Organic and Inorganic Fertilizers on the Antioxidant Enzyme Activity and Yield of Maize Leaves

Agronomy
The aim of this study was to explore the characteristics of the combined application of organic fertilizer and inorganic fertilizer using different tillage methods to delay the senescence of maize leaves.
Guangming Xie, Min Liang, Pei Chen, Chang Zhang, Mingyuan Fan, Chuangyun Wang, Li Zhao   +6 more
doaj   +1 more source

Application of Organic Fertilizer Tithonia Plus to Control Iron Toxicity and Reduce Commercial Fertilizer Application on New Paddy Field [PDF]

, 2012
Ferrous toxicity is a one of the problems most often found in lowland rice systems in tropical and sub-tropical regionespecially in new paddy field (NPF) on Ultisols and Oxisols.
Agustian, A. (Agustian), Hakim, N. (Nurhajati), Mala, Y. (Yanti)   +2 more
core  

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity

Advanced Science, EarlyView.
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye, Jialiang Kuang, Colin T. Bates, Arthur Escalas, Daliang Ning, Liyou Wu, Suo Liu, Sihang Deng, Jiesi Lei, Xiangwen Chen, Jennifer Pett‐Ridge, Malay Saha, Lauren Hale, Gangsheng Wang, Renmao Tian, Ying Fu, Yu Tang, Mary Firestone, Jizhong Zhou, Yunfeng Yang   +19 more
wiley   +1 more source

Efecto de diferentes dosis de fertilizante compuesto en la calidad del pasto kikuyo (Pennisetum clandestinum Hochst. Ex Chiov.)

Pastos y Forrajes
Se evaluó el efecto de un fertilizante químico compuesto (N-P2O5-K2O, 20-5-5), aplicado en dos formas (sólida y líquida), en algunos indicadores de la calidad del pasto kikuyo (Pennisetum clandestinum); el estudio se realizó en la hacienda La Montaña ...
Ana C Mejía-Taborda, R Ochoa-Ochoa, Marisol Medina-Sierra   +2 more
doaj  

Agri-Environmental Program Compliance in a Heterogeneous Landscape [PDF]

Heterogeneity of agricultural landscapes may necessitate the use of spatially targeted instrument combinations to implement the social optimum. But compliance with these policies may require costly enforcement.
Lankoski, Jussi E., Lichtenberg, Erik, Ollikainen, Markku   +2 more
core   +1 more source

Opinions on biogas in organic farming [PDF]

, 2011
The application of biogas technologies in organic farming involves many considerations: Benefits like improved fertilizer supply and fossil fuel savings are opposed to concerns about economical risks and incompliance with organic principles.
Heiske, Stefan, Østergård, Hanne
core