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Evaluation of the Antihyperglycemic efficacy of the roots of Ferula orientalis L.: An in vitro to in vivo assessment

Fìtoterapìâ
Decoctions of Ferula orientalis L. (Apiaceae), have been traditionally used to lower blood glucose levels (BGLs). After in vitro enzyme inhibition tests on the dichloromethane extracts of the roots (FOD) and the methanol extract of the roots (FOM), isolation studies were carried out on the FOD extract.
Seçkin Engin   +2 more
exaly   +3 more sources

Determination of genotoxic and antigenotoxic properties of essential oil from Ferula orientalis L. using Ames/Salmonella and E. coli WP2 bacterial test systems

Toxicology and Industrial Health, 2014
The essential oils having many application fields such as medicine, flavoring, cosmetics are natural products obtained from aromatic plants. As the natural products of Ferula species have a wide range of use in folk medicine, this study was planned to evaluate the mutagenic and antimutagenic activities of essential oils of leaves and flowers of Ferula ...
Mehmet Karadayi   +2 more
exaly   +3 more sources

Comparison of the essential oils of Ferula orientalis L., Ferulago sandrasica Peşmen and Quézel, and Hippomarathrum microcarpum Petrov and their antimicrobial activity Ferula orientalis L., Ferulago sandrasica Peșmen ve Quézel ve Hippomarathrum microcarpum Petrov’un Uçucu yağ ve antimikrobiyal Etkilerinin Karşılaştırılması

2019
Objectives: To determine the chemical composition and antimicrobial activity of the essential oils of the aerial parts of Ferula orientalis L., roots of Ferulago sandrasica Pesmen and Quezel, and aerial parts of Hippomarathrum microcarpum Petrov.
Goger, Gamze   +5 more
openaire   +1 more source

Ferula orientalis Extract Induces Mitochondrial Apoptosis Through Redox Modulation in MDA-MB-231 Triple-Negative Breast Cancer Cells

ODÜ Tıp Dergisi
Objective: Triple-negative breast cancer (TNBC) is an aggressive molecular subtype of breast cancer characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression. Due to limited targeted therapeutic options and intrinsic redox adaptations, TNBC cells exhibit increased oxidative vulnerability, making redox modulation a ...
openaire   +1 more source

Türkiye’de yetişen Ferula orientalis L’nin toprak üstü ve kök ekstrelerinin streptozotosin ile indüklenen diyabetik sıçanlarda erektil disfonksiyon üzerine etkisi

2018
Apiaceae familyasına ait Ferula L. cinsinin Türkiye’de 22 türü yetişmekte olup bu türlerin 13'ü endemiktir ve bu cins zamk-reçine bakımından zengindir. Ferula türleri Türkiye’nin çeşitli yörelerinde “çakşır, çakşırotu, helizan, çağşır, kıngor, çağ vb.” adlarıyla bilinmektedir. Türkiye’de F. orientalis “heliz” adıyla bilinir ve karminatif, sedatif,
KARAKAYA, Songül   +3 more
openaire   +2 more sources

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