Results 201 to 210 of about 1,496,592 (352)

Acetaldehyde-Mediated Neurotoxicity: Relevance to Fetal Alcohol Spectrum Disorders [PDF]

, 2011
Ming Tong, Lisa Longato, Quynh-GiaoLy Nguyen, William Chen, Amy Spaisman, Suzanne M. de la Monte   +5 more
openalex   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Rat models of fetal alcohol spectrum disorders for studying the critical role of cerebellar damage: A scoping review. [PDF]

Alcohol Clin Exp Res (Hoboken)
Nogales F, Jotty K, Pascual-Vaca D, Gallego-López MDC, Carreras O, Ojeda ML.   +5 more
europepmc   +1 more source

Addressing Fetal Alcohol Spectrum Disorder in Aboriginal Communities

, 2014
Lorian Hayes, Judith Katzenellenbogen, Maureen Carter   +2 more
openalex   +1 more source

Reduced DNA methylation at the PEG3 DMR and KvDMR1 loci in children exposed to alcohol in utero: a South African Fetal Alcohol Syndrome cohort study [PDF]

, 2015
Matshane L. Masemola, Lize van der Merwe, Zané Lombard, Denis Viljoen, Michèle Ramsay   +4 more
openalex   +1 more source

Fetal alcohol spectrum disorders

Nature Reviews Disease Primers, 2017
Tom Donaldson, Carolyn Hartness, Suzie Kuerschner, N. Molly, Millians, Alexandra Perez, Catherine Lipman, Christopher Gomez, Alison Crichton, Lauren Perovsek, Mary Capili, Jasmin Barrett, Sarah Hamersma, Natalie N Brown, Stephen Greenspan, Jaco Leana Olivier, Gidion Louw, Mandi Broodryk, Christie L. M. Petrenko, Lynn Cole, Julianne Myers, C. Tapparello, H. Olson, Raja Mukherjee, Alan Price, Catherine Lebel, David Junior Gilbert, L. V. Cox, Ana C. Hanlon-Dearman, Erin Klimpke, M. Harvie, Scoping Chloe Wilson, Elizabeth Elliott, Erika Makowecki, Olivia Weeks, A. Mahnke, C. Coles, Blake Gimbel, Sarah Mattson, Michael Suttie, Miguel del Campo, Jeffrey Wozniak, Christiano Tapparello, Agata Cichoń-Chojnacka, Malgosia Tomanik, Daniel D Savage, Derek A. Hamilton, Michelle Kuhn, Emily Fox, E. Olson, L. Huang-Storms, Stewart McDougall, Suzanne O'Rourke, Carl Young, Susan Stoner, Mexico Kenya Poland, K. Anna, Esteban Dyląg, Dennis Hernandez, Moogi, March Laura Hellenbrand SATURDAY, Edward Riley, Nancy Poole, Sophie Harrington, Jacqueline Bowden, Ali Ruprecht, Brandon K. Attell, Amanda Kudis, Elizabeth H Lee, Ilse Rivera, Paul Patterson, K. Apilado, Eric Flake, Parker J. Holman, C. Raineki, Tamara S. Bodnar, Tania L Goddard, Michael Jeffery, Brittenany Gillespie, Rhonda Romero, Valerie D Guimaraes, Annika Montag, Laura Bousquet   +82 more
semanticscholar   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Third Annual Workshop on Fetal Alcohol Spectrum Disorders Prevention and Clinical Guidelines Research: Supports, Interventions, and Therapies for the Family and Child. [PDF]

BMC Proc
Koehlmoos TP, Lee E, Rivera I, Wisdahl J, Donaldson T.   +4 more
europepmc   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Prevalence of Fetal Alcohol Spectrum Disorders: A Pilot Study in Western Sweden. [PDF]

Acta Paediatr
Landgren V, Knez R, Karlsson D, Fernmo S, Johnson M, Svensson L, Landgren M.   +6 more
europepmc   +1 more source