Results 211 to 220 of about 1,496,592 (352)

Defining an Adult Screener for Fetal Alcohol Spectrum Disorder: A Study of Court Populations

, 2020
Allison Mushlitz
openalex   +1 more source

Interventions in fetal alcohol spectrum disorders: An international perspective.

European Journal of Medical Genetics, 2017
Christie L. M. Petrenko, Michelle E. Alto   +1 more
semanticscholar   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Machine learning-driven blood biomarker profiling and EGCG intervention in fetal alcohol spectrum disorder. [PDF]

Int J Clin Health Psychol
Ramos-Triguero A, Navarro-Tapia E, Vieiros M, Martínez L, García-Algar Ó, Andreu-Fernández V.   +5 more
europepmc   +1 more source

Malocclusion Can Give Additional Hints for Diagnosis of Fetal Alcohol Spectrum Disorder [PDF]

, 2018
Moritz Blanck‐Lubarsch, S Flieger, Reinhold Feldmann, Christian Kirschneck, Cristina Sauerland, Ariane Hohoff   +5 more
openalex   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Overcoming barriers to care for individuals with fetal alcohol spectrum disorder: challenges and solutions in New Mexico and beyond. [PDF]

Front Pediatr
Gibson AC, Velhagen JM, Jaffe T, Hill DE, Moriarta ML, Valenzuela CF.   +5 more
europepmc   +1 more source

Profile of children diagnosed with a fetal alcohol spectrum disorder: A retrospective chart review

Drug and Alcohol Review, 2017
N. Reid, Doug Shelton, Judith Warner, F. O'Callaghan, S. Dawe   +4 more
semanticscholar   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source