Results 221 to 230 of about 1,496,592 (352)

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

open access: yesAdvanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu   +8 more
wiley   +1 more source

Impaired Placentation in Fetal Alcohol Syndrome

open access: green, 2007
Füsun Gündoğan   +7 more
openalex   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

open access: yesAdvanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao   +16 more
wiley   +1 more source

Importance of Fetal Alcohol Spectrum Disorders Prevention and Intervention. [PDF]

open access: yesSubst Use Addctn J
Donaldson T   +5 more
europepmc   +1 more source

The Economic Burden of Fetal Alcohol Spectrum Disorder in Canada in 2013.

open access: yesAlcohol and Alcoholism, 2016
S. Popova, S. Lange, L. Burd, J. Rehm
semanticscholar   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

open access: yesAdvanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du   +6 more
wiley   +1 more source

Cobalamin Status Among Patients with Fetal Alcohol Spectrum Disorder (FASD)-A Preliminary Study. [PDF]

open access: yesNutrients
Król-Dykas M   +9 more
europepmc   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang   +10 more
wiley   +1 more source

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