Results 171 to 180 of about 68,904 (253)

Neurovascular Disorders in Pregnancy: Prevalence, Clinical Assessment and Management—A Review of the Literature

open access: yesThe Obstetrician &Gynaecologist, EarlyView.
ABSTRACT Key Content Neurovascular conditions in pregnancy are rare but are associated with poor maternal and fetal outcomes. This review covers the prevalence, clinical presentation, diagnosis and management of neurovascular disorders in pregnancy. The approach to clinical assessment and investigation of pregnant women with acute or changing chronic ...
Amy Newnham   +5 more
wiley   +1 more source

Non-immune hydrops fetalis (NIHF): diagnostic evaluation and lessons learned from a case series. [PDF]

open access: yesFuture Sci OA
Al Hassan J   +6 more
europepmc   +1 more source

Pediatric transfusion camp: Developing, piloting and evaluation of a Canadian national pediatric transfusion medicine curriculum

open access: yesTransfusion, EarlyView.
Abstract Background Standardized post‐graduate education in pediatric transfusion medicine remains limited. The objective of this study was to adapt an adult transfusion education program, Transfusion Camp, to include pediatric content and assess knowledge improvement in pediatric subspecialty trainees.
Ines Zuna   +14 more
wiley   +1 more source

Comparison of four different in vitro assays for prediction of potential RBC antibody clinical significance

open access: yesTransfusion, EarlyView.
Abstract Background The monocyte monolayer assay (MMA) uses monocytes, but it is known that antibody‐mediated hemolysis occurs in macrophages. Whether the use of macrophages would improve the predictive capacity of the MMA is unclear. Also, it is unclear if RBC alloantibodies contribute to hemolysis via antibody‐dependent cellular cytotoxicity (ADCC ...
Yeniley Ruiz Noa   +6 more
wiley   +1 more source

Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Effective chemotherapy for canine histiocytic sarcoma (CHS) has yet to be established. In our previous study, CHS cell lines were subclassified into two groups based on their gene expression profiles: Group A and Group B. This study aimed to identify novel therapeutic agents that are effective against each CHS subgroup, and we performed high ...
Hiroki Sakuma   +6 more
wiley   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson   +1 more
wiley   +1 more source

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa   +8 more
wiley   +1 more source

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