Results 171 to 180 of about 490,987 (248)

Fetal thrombocytopenia in pregnancies complicated by fetal anemia due to red-cell alloimmunization: cohort study and meta-analysis. [PDF]

open access: yesJ Perinatol, 2019
Rosenbloom JI   +6 more
europepmc   +1 more source

Pregnancy‐Related Risk and Birth Setting Trends: Insights From Indonesian Demographic Health Survey Data

open access: yesBirth, EarlyView.
New analysis from 15 years of Indonesian Demographic Health Survey Data has identified a shift from home birth to hospital birth. However, 65% of women who gave birth in hospital had no risk factors, while 13% of women who gave birth at home did report pregnancy‐related risk factors.
Kai Hodgkin   +2 more
wiley   +1 more source

Exploring the Passive Second Stage of Labour and Related Perinatal Outcomes in a Physiological Cohort

open access: yesBirth, EarlyView.
ABSTRACT Background The passive second stage of labor has been increasingly recognized as a normal phase of labor. However, it remains poorly studied, especially in healthy women. This study aims to assess the passive phase in healthy laboring women and maternal and neonatal outcomes.
Lucia Zagra   +6 more
wiley   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

open access: yesBritish Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi   +3 more
wiley   +1 more source

Predict less, prevent more: A familiar mantra for sickle cell anaemia?

open access: yesBritish Journal of Haematology, EarlyView.
Commentary on: Sommet J, Boizeau P, Haouari Z, et al. Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia. Br J Haematol. 2026 (Online ahead of print). doi: 10.1111/bjh.70726.
Charles T. Quinn
wiley   +1 more source

Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia

open access: yesBritish Journal of Haematology, EarlyView.
Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet   +16 more
wiley   +1 more source

Parvovirus B19 infections in paediatric sickle cell disease patients: Genotype and hydroxyurea treatment influence disease severity

open access: yesBritish Journal of Haematology, EarlyView.
Summary In patients with sickle cell disease (SCD), parvovirus B19 infection (B19V) leads to acute anaemia (aplastic crisis), but may also be associated with other serious complications. We retrospectively analysed clinical data from paediatric SCD patients with B19V infections between 2023 and 2025, including symptoms, laboratory parameters ...
Matthias Bleeke   +42 more
wiley   +1 more source

Carrying a crisis: The risk of a painful sickle cell crisis during pregnancy

open access: yesBritish Journal of Haematology, EarlyView.
Commentary on: Auger et al. Sickle cell anaemia with and without crises: An observational study of pregnancy outcomes. Br J Haematol 2026 (Online ahead of print). doi: 10.1111/bjh.70837.
Bart J. Biemond
wiley   +1 more source

Sickle cell anaemia with and without crises: An observational study of pregnancy outcomes

open access: yesBritish Journal of Haematology, EarlyView.
Summary We assessed the pregnancy outcomes of patients with sickle cell crises. We carried out a retrospective study of 2 698 556 pregnancies in Quebec, Canada between 1989 and 2022. The primary exposure was sickle cell anaemia with crisis during or outside of pregnancy. Outcomes included severe maternal morbidity and other pregnancy complications.
Nathalie Auger   +8 more
wiley   +1 more source

Genetics in Heterotaxy: A Case Series and Literature Review on DNAH9, PKD1L1, MMP21, and GDF1

open access: yesClinical Genetics, EarlyView.
Integrating trio‐based genomic sequencing with detailed clinical evaluation across seven French–Vietnamese heterotaxy cases alongside a review of 108 published patients reveals strong genotype–phenotype correlations. Variants in DNAH9, PKD1L1, MMP21, and GDF1 define a broad spectrum from isolated situs inversus to complex conotruncal heart defects and ...
Thi Bich Tuyen Ho   +23 more
wiley   +1 more source

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