Results 61 to 70 of about 129,591 (344)

Identification and characterization of mechanistically distinct inducers of gamma-globin transcription [PDF]

, 2003
Inhibition of HbS polymerization is a major target for therapeutic approaches in sickle cell anemia.
Asano, Asano, Atweh, Baliga, Berg, Chada, Chada, Charache, Clegg, Darkin-Rattray, de Wet, DeSimone, Fibach, Grosveld, Gumucio, Gumucio, Han, Holmes, Jane, Kollias, Koshy, Luethy, McDonagh, Mosser, Ney, Noguchi, Pace, Park, Poillon, Prestera, Riggs, Rutherford, Talbot, Tuan, Turner, Wijgerde, Witt, Wood, Yang, Zhou   +39 more
core   +2 more sources

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source

A Novel Therapeutic Strategy for Bone Marrow Failure: Niche Rejuvenation Using Costal Cartilage‐Derived Stem Cells

Advanced Science, EarlyView.
CDSCs exhibit the potential to differentiate into endothelial cells, vascular pericytes, and osteoblasts. These differentiated cells are capable of secreting additional pro‐hematopoietic cytokines. Furthermore, CDSCs can inhibit apoptosis and reduce DNA damage in injured hematopoietic stem and progenitor cells (HSPCs, including RHSCs and RHPCs), while ...
Rui Dong, Zhiguo Ling, Pengyuan Fan, Debao Li, Jinsong Wang, Wenjiong Shi, Rui Zuo, Runfeng Chen, Xuemin Sun, Lang Xiao, Yushi Ran, Shucheng Huang, Yi Tian, Chao Zhang, Yuzhang Wu, Bing Ni, Yi Zhang   +16 more
wiley   +1 more source

EL DOPPLER DE LA ARTERIA CEREBRAL MEDIA REEMPLAZA A LA ESPECTROFOTOMETRÍA DEL LÍQUIDO AMNIÓTICO COMO EL ESTÁNDAR EN EL MANEJO DE LA ISOINMUNIZACIÓN FETAL

Revista Chilena de Obstetricia y Ginecología, 2007
La anemia fetal puede ser una condición devastadora para el feto. La principal causa de anemia fetal es la sensibilización materna por el antígeno D.
David Vargas C, Jorge Carvajal C
doaj  

Intrauterine transfusion under fetal analgesia: the evaluation of perinatal outcomes

Frontiers in Pain Research
IntroductionIntrauterine transfusion is the treatment for fetal anemia resulting from maternal alloimmunization, infections (parvovirus B19 and cytomegalovirus), single demise of a monochorionic twin, chorioangioma, and other rare conditions.
Mariano Lanna, Mariano Lanna, Daniela Casati, Daniela Casati, Chiara Bianchi, Chiara Bianchi, Stefano Faiola, Stefano Faiola, Arianna Laoreti, Arianna Laoreti, Francesco Cavigioli, Francesco Cavigioli, Valeria Savasi, Gianluca Lista, Gianluca Lista   +14 more
doaj   +1 more source

Cálculo do volume de sangue necessário para a correção da anemia fetal em gestantes isoimunizadas Blood volume calculation required for the correction of fetal anemia in pregnant women with alloimmunization

Revista Brasileira de Ginecologia e Obstetrícia, 2008
OBJETIVO: obter uma equação capaz de estimar o volume de concentrado de hemácias a ser infundido para correção da anemia em fetos de gestantes portadoras de isoimunização pelo fator Rh, baseado em parâmetros alcançados durante a cordocentese prévia à ...
Mônica Deolindo Santiago, Cezar Alencar de Lima Rezende, Antônio Carlos Vieira Cabral, Henrique Vitor Leite, Zilma Nogueira dos Reis Vitral, Isabela Melo Apocalypse   +5 more
doaj   +1 more source

Lipid-soluble Vitamins A, D, and E in HIV-Infected Pregnant women in Tanzania. [PDF]

, 2010
There is limited published research examining lipid-soluble vitamins in human immunodeficiency virus (HIV)-infected pregnant women, particularly in resource-limited settings.
A Coutsoudis, A Prentice, AJ Roodenburg, B Specker, CM Veldman, D J Hunter, D Spiegelman, D Spiegelman, D Suharno, E Hertzmark, E L Giovannucci, E Villamor, EM Knight, F Ahmed, F M Mugusi, G Antelman, G I Msamanga, G Mulokozi, GA Keverenge-Ettyang, GC Di Renzo, GT Bondevik, H Babbe, H Friis, J Reichrath, JM Baeten, KN Evans, KP West Jr, LC Chappell, LC Stene, LH Allen, LM Bodnar, MF Holick, MF Picciano, MK Horwitt, MR Loeken, O Miettinen, P Christian, P Haga, P Zvandasara, PT Liu, R Kupka, RD Semba, RJ Stoltzfus, S Aboud, S de Pee, S Durrleman, S Mehta, S Yang, SG Hinderaker, SN Meydani, TO Scholl, US Govindarajulu, W Fawzi, W Urassa, W W Fawzi, WHO, WW Fawzi, WW Fawzi, Y Wang, Y Wondmikun, Z Bar-Shavit, Z Zaman   +61 more
core   +1 more source

GDF15 Ameliorates Deoxynivalenol‐Induced Anemia by Resolving Ribosomal Stress–Mediated Erythropoietic Arrest

Advanced Science, EarlyView.
Deoxynivalenol induces anemia by disrupting hematopoietic homeostasis and impairing erythroid lineage commitment and differentiation via ribosomal stress–mediated G1/S cell cycle arrest. GDF15 supplementation alleviates this arrest through the β‐catenin–Myc–p21 signaling axis, highlighting GDF15 as a potential therapeutic target for DON‐induced ...
Yan Li, Peijun Jia, Jingxin Zhang, Huan Zhang, Bing Li, Jiawei Chang, Yating Li, Longzhen Zhao, Yazhe Zhen, Tingting Zheng, Yuanlin Xu, Xiuli An, Shijie Zhang   +12 more
wiley   +1 more source

ANEMIA FETAL Y MANEJO

Revista Peruana de Ginecología y Obstetricia, 2015
La anemia fetal es la disminución de la concentración de hemoglobina (Hb) por debajo de 2 desviaciones estándar o <0,84 MoM con respecto a la media poblacional. Si bien es cierto que el estándar de oro para su diagnóstico es la medición de la Hb fetal mediante cordocentesis percutánea, el pico de velocidad sistólica de la arteria cerebral media (PVS
openaire   +5 more sources

Speciation in the baboon and its relation to gamma-chain heterogeneity and to the response to induction of HbF by 5-azacytidine [PDF]

, 1984
In the baboon (Papio species), the two nonallelic gamma-genes produce gamma-chains that differ at a minimum at residue 75, where isoleucine (I gamma-chain) or valine (V gamma) may be present.
DeSimone, Joseph, Espinueva, Zenaida, Hall, Lemuel, Huynh, Van, Schroeder, W. A., Shelton, J. Roger, Shelton, Joan B., Zwiers, David   +7 more
core