Results 21 to 30 of about 616,498 (259)
Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A
Frontiers in Bioengineering and Biotechnology, 2021 Microfluidic technology enables recapitulation of organ-level physiology to answer pertinent questions regarding biological systems that otherwise would remain unanswered.
Brady Trevisan +13 more
doaj +1 more source
Clinics and PracticeBackground: Neonatal bone mass may potentially be influenced by existing maternal vitamin D (25(OH)D) levels. Few studies evaluated maternal vitamin D deficiency (VDD) with neonatal anthropometrics such as weight, height and head circumference (HC ...
Artemisia Kokkinari +4 more
doaj +1 more source
Analysis of the microbiome based on 16S rRNA gene signature in women with preterm versus term birth
Reproductive and Developmental Medicine, 2021 Objective: To characterize and compare the microbiome signature in the maternal, intrauterine, and fetal environments and the associated bacterial species in women who experienced preterm birth and term birth. Methods: A total of 140 women with singleton
Jiao Yu +4 more
doaj +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2016 Objective: Assessment of the fetal medulla oblongata volume (MOV) and blood flow might be important in the evaluation of fetal brain growth. We used three-dimensional power Doppler ultrasound (3DPDUS) to assess the fetal MOV and blood flow index in ...
Ing-Luen Shyu +7 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Pathogens in Maternal Blood and Fetal Cord Blood Using Q-Pcr Assay
Taiwanese Journal of Obstetrics & Gynecology, 2006 Objective: To evaluate the rates of infection of asymptomatic fetuses and mothers through fetal cord blood and maternal blood examination results. Materials and Methods: Quantitative PCR (Q-PCR) was used to detect pathogens in maternal peripheral blood ...
Guang Qiong Hou +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Clinics and PracticeBackground: Few studies have correlated maternal and neonatal Vit D (25(OH)D) levels at birth in Greece. We investigated this potential association, taking into account the administration or not of low doses (400–800 IU) of prenatal Vit D supplements ...
Artemisia Kokkinari +6 more
doaj +1 more source
Defining the Optimal FVIII Transgene for Placental Cell-Based Gene Therapy to Treat Hemophilia A
Molecular Therapy: Methods & Clinical Development, 2020 The delivery of factor VIII (FVIII) through gene and/or cellular platforms has emerged as a promising hemophilia A treatment. Herein, we investigated the suitability of human placental cells (PLCs) as delivery vehicles for FVIII and determined an optimal
Nadia El-Akabawy +14 more
doaj +1 more source