OBJECTIVES: To assess whether the offspring of UK veterans of the first Gulf war are at increased risk of fetal death or congenital malformation. METHOD: This was a retrospective reproductive cohort study of UK Gulf war veterans and a demographically ...
Davies, Graham+6 more
core +1 more source
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel+9 more
wiley +1 more source
Histórias de perdas fetais contadas por mulheres: estudo de análise qualitativa
OBJETIVO: (Re)conhecer o significado da perda fetal para mulheres que vivenciaram a experiência, a partir da compreensão do processo de gravidez, com base em seus relatos.
Alba Lúcia Dias dos Santos+2 more
doaj
Bacterial lipopolysaccharide-mediated fetal death. Production of a newly recognized form of inducible cyclooxygenase (COX-2) in murine decidua in response to lipopolysaccharide. [PDF]
Robert M. Silver+6 more
openalex +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan+6 more
wiley +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao+10 more
wiley +1 more source
Fetal and Neonatal Deaths Resulting from Chikungunya Virus Infection During Pregnancy: A Case Series
Ana Cristina Pedrosa Do Monte,1,2,* Heloisa Ramos Lacerda1,3,* 1Department of Tropical Medicine, Center for Medical Sciences, Federal University of Pernambuco, Recife, Pernambuco, Brazil; 2I Regional Health Management of the State of Pernambuco ...
Monte ACP, Lacerda HR
doaj
3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht+5 more
wiley +1 more source
Chronic Prenatal Exposure to Carbon Monoxide Results in a Reduction in Tyrosine Hydroxylase-Immunoreactivity and an Increase in Choline Acetyltransferase-Immunoreactivity in the Fetal Medulla: Implications for Sudden Infant Death Syndrome [PDF]
Mary Tolcos+3 more
openalex +1 more source