Results 121 to 130 of about 755,013 (356)

Miscarriage, stillbirth and congenital malformation in the offspring of UK veterans of the first Gulf war.

open access: yes, 2004
OBJECTIVES: To assess whether the offspring of UK veterans of the first Gulf war are at increased risk of fetal death or congenital malformation. METHOD: This was a retrospective reproductive cohort study of UK Gulf war veterans and a demographically ...
Davies, Graham   +6 more
core   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Histórias de perdas fetais contadas por mulheres: estudo de análise qualitativa

open access: yesRevista de Saúde Pública
OBJETIVO: (Re)conhecer o significado da perda fetal para mulheres que vivenciaram a experiência, a partir da compreensão do processo de gravidez, com base em seus relatos.
Alba Lúcia Dias dos Santos   +2 more
doaj  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Fetal and Neonatal Deaths Resulting from Chikungunya Virus Infection During Pregnancy: A Case Series

open access: yesInternational Medical Case Reports Journal
Ana Cristina Pedrosa Do Monte,1,2,* Heloisa Ramos Lacerda1,3,* 1Department of Tropical Medicine, Center for Medical Sciences, Federal University of Pernambuco, Recife, Pernambuco, Brazil; 2I Regional Health Management of the State of Pernambuco ...
Monte ACP, Lacerda HR
doaj  

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht   +5 more
wiley   +1 more source

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