Results 1 to 10 of about 576,100 (268)

Fetal origins of cardiovascular disease [PDF]

Annals of Medicine, 1999
Low birthweight, thinness and short body length at birth are now known to be associated with increased rates of cardiovascular disease and non-insulin dependent diabetes in adult life. The fetal origins hypothesis proposes that these diseases originate through adaptations which the fetus makes when it is undernourished.
openaire   +3 more sources

Fetal Origins of Adult Disease [PDF]

Current Problems in Pediatric and Adolescent Health Care, 2011
Dr. David Barker first popularized the concept of fetal origins of adult disease (FOAD). Since its inception, FOAD has received considerable attention. The FOAD hypothesis holds that events during early development have a profound impact on one's risk for development of future adult disease. Low birth weight, a surrogate marker of poor fetal growth and
Kara, Calkins, Sherin U, Devaskar
openaire   +2 more sources

Identifying risk factors for perinatal death at Tororo District Hospital, Uganda: a case-control study

BMC Pregnancy and Childbirth, 2020
Background Sub-Saharan Africa faces a disproportionate burden of perinatal deaths globally. However, data to inform targeted interventions on an institutional level is lacking, especially in rural settings. The objective of this study is to identify risk
Martha A. Tesfalul, Paul Natureeba, Nathan Day, Ochar Thomas, Stephanie L. Gaw   +4 more
doaj   +1 more source

Spatiotemporal Study of COVID-19 in Fars Province, Iran, October-November 2020: Establishment of Early Warning System

Canadian Journal of Infectious Diseases and Medical Microbiology, 2022
Background. Using time series and spatiotemporal analyses, this study aimed to establish an Early Warning System (EWS) for COVID-19 in Fars province Iran. Methods.
Ali Semati, Azimeh Zare, Marjan Zare, Alireza Mirahmadizadeh, Mostafa Ebrahimi   +4 more
doaj   +1 more source

Fetal programming and future disease [PDF]

Revista do Hospital das Clínicas, 2004
Recent epidemiological studies have demonstrated a close relationship between low birth weight and a high predisposition to arterial hypertension, hyperlipidemia and non-insulin-dependent diabetes in adulthood. These findings may coexist as Syndrome X, more recently named as Metabolic Syndrome, and understood as precursory of coronary heart disease and
openaire   +3 more sources

Clinical application of cervical shear wave elastography in predicting the risk of preterm delivery in DCDA twin pregnancy

BMC Pregnancy and Childbirth, 2022
Background Limited studies have used cervical shear wave elastography (SWE) as a tool to investigate the predictive effect of cervical changes on preterm delivery (PTD) in twin pregnancy.
Jimei Sun, Nan Li, Wei Jian, Dingya Cao, Junying Yang, Min Chen   +5 more
doaj   +1 more source

The impact of gravidity, symptomatology and timing of infection on placental malaria

Malaria Journal, 2020
Background Placental malaria is associated with increased risk of adverse perinatal outcomes. While primigravidity has been reported as a risk factor for placental malaria, little is known regarding the relationship between gravidity, symptomatology and ...
Erin E. Tran, Morgan L. Cheeks, Abel Kakuru, Mary K. Muhindo, Paul Natureeba, Miriam Nakalembe, John Ategeka, Patience Nayebare, Moses Kamya, Diane Havlir, Margaret E. Feeney, Grant Dorsey, Stephanie L. Gaw   +12 more
doaj   +1 more source

Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood

Journal of Chemistry, 2022
Prenatal diagnosis is an important means of early diagnosis of genetic diseases, which can effectively reduce the risk of birth defects. Free fetal cells, as a carrier of intact fetal genetic material, provide hope for the development of high-sensitivity
Ying Tang, Qiaojin Tang, Haiyan Luo, Xuehui Zhang, Qiuyu Chen, Wenying Tang, Ting Wang, Lihua Yang, Hongwu Liao   +8 more
doaj   +1 more source

An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia

Stem Cell Research, 2021
Achondroplasia (ACH; MIM #100800) is an autosomal dominant genetic disease caused by gain-of-function mutations in FGFR3 gene and results in short-limb dwarfism.
Nan Li, Sheng Mou Lin, Yingting Li, Jimei Sun, Luting Zhang, Min Chen   +5 more
doaj   +1 more source

Oxidative stress in pediatric diseases associated with the origin of life and growth and development

Frontiers in Cell and Developmental Biology
The presence of oxidative stress and an imbalance in antioxidant mechanisms have been demonstrated in numerous diseases. Furthermore, mounting evidence suggests that the occurrence, progression, and prognosis of certain pediatric diseases linked to the ...
Bo Zheng, Jianhua Fu
doaj   +1 more source