Results 1 to 10 of about 10,284,356 (372)

Fetal nutrition and adult disease [PDF]

The American Journal of Clinical Nutrition, 2000
Recent research suggests that several of the major diseases of later life, including coronary heart disease, hypertension, and type 2 diabetes, originate in impaired intrauterine growth and development. These diseases may be consequences of "programming," whereby a stimulus or insult at a critical, sensitive period of early life has permanent effects ...
Keith M. Godfrey, David J.P. Barker
semanticscholar   +5 more sources

Oxidative stress in pediatric diseases associated with the origin of life and growth and development [PDF]

Frontiers in Cell and Developmental Biology
The presence of oxidative stress and an imbalance in antioxidant mechanisms have been demonstrated in numerous diseases. Furthermore, mounting evidence suggests that the occurrence, progression, and prognosis of certain pediatric diseases linked to the ...
Bo Zheng, Jianhua Fu
doaj   +2 more sources

Elevated fetal steroidogenic activity in autism [PDF]

Molecular Psychiatry, 2014
Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor.
Abdallah, M W, Auyeung, B, Baron-Cohen, S, Chakrabarti, B, Cohen, A S, Hougaard, D M, Lombardo, M V, Melgaard, L, Nørgaard-Pedersen, B, Ruta, L   +9 more
core   +2 more sources

Maternal-Fetal Inflammation in the Placenta and the Developmental Origins of Health and Disease

Frontiers in Immunology, 2020
Events in fetal life impact long-term health outcomes. The placenta is the first organ to form and is the site of juxtaposition between the maternal and fetal circulations.
Jeffery A. Goldstein, Kelly Gallagher, Celeste Beck, Rajesh Kumar, Alison D. Gernand   +4 more
doaj   +2 more sources

Beyond liver cancer, more application scenarios for alpha-fetoprotein in clinical practice

Frontiers in Oncology, 2023
Alpha-fetoprotein (AFP) is a commonly used clinical biomarker. Before 1970, the two-way agar diffusion method was mainly used, and the specificity of AFP in the diagnosis of primary liver cancer was satisfactory. However, its positivity rate was not very
Chenyu Ma, Yuexinzi Jin, Yuhan Wang, Huaguo Xu, Jiexin Zhang   +4 more
doaj   +1 more source

SARS-CoV-2 Placentitis Associated With B.1.617.2 (Delta) Variant and Fetal Distress or Demise

Journal of Infectious Diseases, 2022
There is limited information on the specific impact of maternal infection with the SARS-CoV-2 B.1.617.2 (delta) variant on pregnancy outcomes. We present 2 cases of intrauterine fetal demise and 1 case of severe fetal distress in the setting of maternal ...
L. Shook, S. Brigida, J. Regan, J. P. Flynn, Abbas Mohammadi, B. Etemad, Molly R. Siegel, M. Clapp, Jonathan Z. Li, D. Roberts, A. Edlow   +10 more
semanticscholar   +1 more source

Utility of a modified vascular corrosion casting technique in the diagnosis of fetal total anomalous pulmonary venous connection

Scientific Reports, 2021
Total anomalous pulmonary venous connection (TAPVC) is a rare congenital cardiac malformation, and prenatal detection of TAPVC malformation remains a challenging. TAPVC can be easily missed or misdiagnosed in prenatal examinations.
Jiaqi Zhang, Wei Feng, Qiaoyue He, Hongzhi Guo, He Zeng, Ziyi Si, Ya Liu, Yu Wang   +7 more
doaj   +1 more source

Protocols for the Evaluation of Neurodevelopmental Alterations in Rabbit Models In Vitro and In Vivo

Frontiers in Toxicology, 2022
The rabbit model is gaining importance in the field of neurodevelopmental evaluation due to its higher similarity to humans in terms of brain development and maturation than rodents.
Laura Pla, Britta Anna Kühne, Britta Anna Kühne, Laia Guardia-Escote, Laia Guardia-Escote, Paula Vázquez-Aristizabal, Paula Vázquez-Aristizabal, Carla Loreiro, Burkhard Flick, Eduard Gratacós, Marta Barenys, Miriam Illa   +11 more
doaj   +1 more source

The Role of Magnesium in Pregnancy and in Fetal Programming of Adult Diseases

Biological Trace Element Research, 2020
Magnesium is an essential trace metal and a necessary factor for multiple biochemical functions in humans. Its role in biology is fundamental in over 600 enzymatic reactions implicated in protein synthesis, mitochondrial functions, neuromuscular activity,
D. Fanni, C. Gerosa, V. Nurchi, M. Manchia, Luca Saba, F. Coghe, G. Crisponi, Yukio Gibo, P. Eyken, V. Fanos, Gavino Faa, Gavino Faa   +11 more
semanticscholar   +1 more source

Electromagnetic fields exposure on fetal and childhood abnormalities: Systematic review and meta-analysis

Open Medicine, 2023
Today, in the modern world, people are often exposed to electromagnetic waves, which can have undesirable effects on cell components that lead to differentiation and abnormalities in cell proliferation, deoxyribonucleic acid (DNA) damage, chromosomal ...
Kashani Zahra Atarodi, Pakzad Reza, Fakari Farzaneh Rashidi, Haghparast Mohammad Sadegh, Abdi Fatemeh, Kiani Zohreh, Talebi Afsaneh, Haghgoo Somaieh Moradi   +7 more
doaj   +1 more source