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Fetal origins of cardiovascular disease

Current Opinion in Pediatrics, 2003
Several epidemiologic studies have shown that intrauterine growth retardation is a risk factor for the development of cardiovascular disease in later life. In this review, we discuss these epidemiologic studies and animal models that have been developed to investigate the pathophysiology of this phenomenon.
Michel, Baum, Luis, Ortiz, Albert, Quan
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Placental Abnormalities and Fetal Disease

Archives of Pediatrics & Adolescent Medicine, 1964
Pediatricians, although caring for newly born infants, often have limited knowledge of abnormalities of the placenta that may affect the infant. Few articles on this subject appear in pediatric journals. Pediatricians gain relevant personal experience indirectly, and in fact, seldom see even grossly abnormal placentas.
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Fetal origins of adult disease

Seminars in Fetal and Neonatal Medicine, 2006
The term 'fetal origins of adult disease' was coined on the basis of the inverse association between low birth weight and blood pressure, adult-onset diabetes, coronary heart disease, and stroke seen in numerous epidemiological studies. However, it seems unlikely that birth weight is involved in causal pathways underlying these observations, and if it ...
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Fetal Echocardiography to Diagnose Fetal Heart Disease

NeoReviews, 2012
Fetal echocardiography plays a central role in the evaluation of fetuses at risk for heart disease. It allows for detection of cardiac malformations, dysrhythmias, and evaluation of cardiac function. Indications for fetal echocardiography span a wide range that extends from the abnormal screening ultrasound in a low-risk pregnancy to the high-risk ...
Jennifer Co-Vu, Tomislav Ivsic
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Frontiers in fetal cardiovascular disease

Pediatric Clinics of North America, 2004
This article reviews the state of the art in prenatal cardiovascular imaging, the elucidation of regional vascular flow patterns in the developing fetus and what can be learned from these flow patterns, the new clinical practice systems being that are being implemented to deal with the fetal patient and its family, and the prospects for fetal surgery.
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The fetal origins of adult disease

Fetal and Maternal Medicine Review, 1994
Recent studies have shown that babies who are small for dates at birth, or who fail to grow in infancy, have, in adult life, raised blood pressure, impaired glucose tolerance, abnormal serum lipids, raised fibrinogen and high death rates from coronary disease, stroke and obstructive lung disease.
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Familial Diseases Revealed by a Fetal Anomaly

Obstetrical & Gynecological Survey, 2006
The recognition of a fetal anomaly can lead to the same diagnosis being made in one of the asymptomatic parents unaware of the problem. We analyzed cases in which the discovery of a fetal anomaly led to the discovery of a genetic familial disorder.Families in which the recognition of a fetal anomaly led to the same diagnosis being made in one of the ...
R, Robyr   +3 more
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Surgically correctable fetal disease

The American Journal of Surgery, 2000
This paper will give an overview of fetal intervention over the last 2 decades. It is interesting to think that what we think of as birth defects are not really such at all. They are defects that become manifest at birth but which have a long and interesting history. As Samuel Taylor Coleridge said, “The history of man for the nine months preceding his
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Human fetal bilirubin levels and fetal hemolytic disease

International Journal of Gynecology & Obstetrics, 1992
The development of secondary fetal anemia in association with maternal red blood cell alloimmunization requires hemolysis. In specimens obtained at the time of a clinically indicated cordocentesis, total and direct umbilical venous bilirubin was measured and the indirect umbilical venous bilirubin calculated in 43 antigen-positive and 30 control ...
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Fetal Heart Disease

2017
Antenatal diagnosis of structural CHD is now established in clinical practice in many countries. As a consequence, fetal cardiology has developed into a specialty on its own right. Extra-cardiac, chromosomal and genetic abnormalities are not uncommon associations, and therefore, a multidisciplinary approach is important when counselling families about ...
Julene S. Carvalho, Olus Api
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