Results 21 to 30 of about 559,832 (299)
Fetal Origins of Adult Disease [PDF]
Current Problems in Pediatric and Adolescent Health Care, 2011 Dr. David Barker first popularized the concept of fetal origins of adult disease (FOAD). Since its inception, FOAD has received considerable attention. The FOAD hypothesis holds that events during early development have a profound impact on one's risk for development of future adult disease. Low birth weight, a surrogate marker of poor fetal growth and
Kara, Calkins, Sherin U, Devaskar
openaire +2 more sources
BMC Pregnancy and Childbirth, 2022 Background Limited studies have used cervical shear wave elastography (SWE) as a tool to investigate the predictive effect of cervical changes on preterm delivery (PTD) in twin pregnancy.
Jimei Sun +5 more
doaj +1 more source
The impact of gravidity, symptomatology and timing of infection on placental malaria
Malaria Journal, 2020 Background Placental malaria is associated with increased risk of adverse perinatal outcomes. While primigravidity has been reported as a risk factor for placental malaria, little is known regarding the relationship between gravidity, symptomatology and ...
Erin E. Tran +12 more
doaj +1 more source
Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood
Journal of Chemistry, 2022 Prenatal diagnosis is an important means of early diagnosis of genetic diseases, which can effectively reduce the risk of birth defects. Free fetal cells, as a carrier of intact fetal genetic material, provide hope for the development of high-sensitivity
Ying Tang +8 more
doaj +1 more source
Stem Cell Research, 2021 Achondroplasia (ACH; MIM #100800) is an autosomal dominant genetic disease caused by gain-of-function mutations in FGFR3 gene and results in short-limb dwarfism.
Nan Li +5 more
doaj +1 more source
Fetal nutrition and adult disease [PDF]
The American Journal of Clinical Nutrition, 2000 Recent research suggests that several of the major diseases of later life, including coronary heart disease, hypertension, and type 2 diabetes, originate in impaired intrauterine growth and development. These diseases may be consequences of "programming," whereby a stimulus or insult at a critical, sensitive period of early life has permanent effects ...
K M, Godfrey, D J, Barker
openaire +2 more sources
Communications Biology, 2023 Decidualization of human endometrial stromal cells (hESCs) is essential for the maintenance of pregnancy, which depends on the fine-tuned regulation of hESCs survival, and its perturbation contributes to pregnancy loss. However, the underlying mechanisms
Yingyu Liang +15 more
doaj +1 more source
Fetal roots of cardiac disease [PDF]
Heart, 2005 In western countries, cardiovascular disease is the leading killer of men and women. In the past decade, it has become increasingly clear that women are just as vulnerable to heart disease as men. In 2004, the number of women with some form of the disease will exceed the number of such men in the USA (www.americanheart.org).
K L, Thornburg, S, Louey
openaire +2 more sources
Oxidative stress in pediatric diseases associated with the origin of life and growth and development
Frontiers in Cell and Developmental BiologyThe presence of oxidative stress and an imbalance in antioxidant mechanisms have been demonstrated in numerous diseases. Furthermore, mounting evidence suggests that the occurrence, progression, and prognosis of certain pediatric diseases linked to the ...
Bo Zheng, Jianhua Fu
doaj +1 more source
Maternal-Fetal Medicine, 2023 . Objective. This study aimed to investigate the immune response of a pregnant woman who recovered from the coronavirus disease 2019 (COVID_RS) by using single-cell transcriptomic profiling of peripheral blood mononuclear cells (PBMCs) and to analyze the
Lili Du +7 more
doaj +1 more source