Results 301 to 310 of about 9,877,071 (357)

Emerging Prognostic and Predictive Biomarkers for Human Cytomegalovirus Infection During Pregnancy: Unmet Needs and Future Perspectives. [PDF]

Viruses
Rotundo S, Tassone MT, Lionello R, Fusco P, Serapide F, Russo A.   +5 more
europepmc   +1 more source

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

Advanced Healthcare Materials, EarlyView.
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou, Johanna Simon, Moritz Beck‐Broichsitter, Gary Davidson, Pavel A. Levkin   +4 more
wiley   +1 more source

Evaluation of fetal cardiac morphology and function in hypertensive disorders of pregnancy using Fetal HQ technology combined with uterine artery ultrasound parameters. [PDF]

Front Cardiovasc Med
Wang L, Fu X, Ren X, Guo Y, Zhou H, Yue H, Song C, Zhang D, Li G, Li W, Zhang P.   +10 more
europepmc   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Can aspartate aminotransferase and platelet distribution width-to-platelet ratio in the first trimester predict fetal macrosomia?: a retrospective case-control study. [PDF]

Rev Assoc Med Bras (1992)
Firatligil FB, Akay A, Ugur M, Sucu S, Akdas Reis Y, Topkara Sucu S, Engin-Ustun Y.   +6 more
europepmc   +1 more source

Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back, Moonkyoung Jeong, Huyen‐Thao Le, Ji‐Ho Park   +3 more
wiley   +1 more source

Prenatal diagnosis of a compound heterozygous variation in the <i>FBXL4</i> gene by trio-WES and imaging monitoring: a case report. [PDF]

Front Genet
Zhai Y, Chen J, Yang S, Wang H, Xiao Y, Liu S.   +5 more
europepmc   +1 more source

Enhancing Ultrasound Power Transfer: Efficiency, Acoustics, and Future Directions

Advanced Materials, EarlyView.
Implantable devices significantly enhance healthcare but are limited by battery life. Ultrasound power transfer technology offers a promising solution for sustainable operation. This review addresses gaps in current research, particularly in sound field analysis and energy efficiency optimization.
Yi Zheng, Zhuomin Zhang, Yanhu Zhang, Qiqi Pan, Xiaodong Yan, Xuemu Li, Zhengbao Yang   +6 more
wiley   +1 more source

The Association of Peripheral Blood Immunoinflammatory Markers with PE and Adverse Outcomes in Preeclampsia: A Retrospective Study. [PDF]

J Inflamm Res
Zhuang Y, Xiao Y, Bai R, Song Y, Lin Z, Yu Y, Chen Q, Wang Z.   +7 more
europepmc   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source