Results 61 to 70 of about 866,572 (335)
The fetal origin of adult diseases
Journal of Obstetrics and Gynaecology, 2003 In the last decade, the development of Barker's hypothesis of fetal programming opened the field for extensive research into the fetal origin of adult diseases. The association between low birth weight, which reflects intrauterine nutritional status, and the development of adult diseases has been confirmed in many studies for type 2 diabetes ...
Mark Walker, B Sallout
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The maternal and fetal origins of cardiovascular disease. [PDF]
Journal of Epidemiology & Community Health, 1992 This chapter presents evidence that restraint of growth and development during critical periods of fetal life and infancy have an important effect on the development of cardiovascular disease.
Christopher Martyn, D. J. P. Barker
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FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
EBioMedicine, 2020 : Background: Disordered folliculogenesis is a core characteristic of polycystic ovary syndrome (PCOS) and androgen receptors (ARs) are closely associated with hyperandrogenism and abnormalities in folliculogenesis in PCOS.
Xia Liu +17 more
doaj +1 more source
Antenatal management of fetal neurosurgical diseases [PDF]
Child's Nervous System, 2017 The advance in the imaging tools during the pregnancy (ultrasound and magnetic resonance) allowed the early diagnose of many fetal diseases, including the neurological conditions. This progress brought the neurosurgeons the possibility to propose treatments even before birth.
Cavalheiro, Sergio UNIFESP +6 more
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An efficient platform for astrocyte differentiation from human induced pluripotent stem cells [PDF]
, 2017 Summary: Growing evidence implicates the importance of glia, particularly astrocytes, in neurological and psychiatric diseases. Here, we describe a rapid and robust method for the differentiation of highly pure populations of replicative astrocytes from ...
Abdelaal, Rawan +13 more
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CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Fetal Health State Detection Using Interval Type-2 Fuzzy Neural Networks
Diagnostics, 2023 Diagnosis of fetal health is a difficult process that depends on various input factors. Depending on the values or the interval of values of these input symptoms, the detection of fetal health status is implemented. Sometimes it is difficult to determine
Rahib Abiyev +3 more
doaj +1 more source
Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation. [PDF]
, 2019 Congenital pulmonary airway malformation (CPAM) is the most common congenital lesion detected in the neonatal lung, which may lead to respiratory distress, infection, and pneumothorax.
Jiang, Yi +9 more
core +3 more sources