Results 101 to 110 of about 1,325,442 (244)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

A Hybrid Deep Learning and Image-like Framework for Fetal Heart Rate Estimation Using Phonocardiography Signals

Mathematics
One of the most important parameters in fetal monitoring is the fetal heart rate (fHR). However, due to the nature of this signal, several non-invasive techniques have been developed for fetal monitoring, including Cardiotocography (CTG), Doppler ...
Ernesto Moya-Albor, Sandra L. Gomez-Coronel, Jorge Brieva, Alberto Lopez-Figueroa, Diego Renza   +4 more
doaj   +1 more source

Variable Flip Angle Optimization for Fetal Brain Imaging With Reduced Specific Absorption Rate

NMR in Biomedicine
Half‐Fourier Acquisition with Single‐Shot Turbo Spin Echo (HASTE) scans are routinely used for fetal brain imaging, but they have a high specific absorption rate (SAR) and can be inefficient due to SAR limits. Here, we have designed an optimized variable
Dominique Franson, Camilo Calixto, Hong-Li Fan, Camilo Jaimes, C. Velasco-Annis, S. Ferraciolli, Cesar Alves, Edward Yang, S. Cauley, A. Gholipour   +9 more
semanticscholar   +1 more source

PCGF1 Promotes the Tumorigenesis of Malignancies Through Upregulating CCDC34 in Glioma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Polycomb group factor 1 (PCGF1) and coiled‐coil domain‐containing protein 34 (CCDC34) have been implicated in tumorigenesis in multiple malignancies. However, their biological functions and prognostic significance in glioma remain poorly defined.
Yuanbing Chen, Jianbing Xiong, Ziran Ou, Tianhao Zhao, Hui Li, Jun Huang, Zhi Tian, Wuyang Cao   +7 more
wiley   +1 more source

Urinary Concentrations of Phthalate Metabolites in Relation to Preeclampsia and Other Hypertensive Disorders of Pregnancy in the Environmental Influences on Child Health Outcomes (ECHO) Program

Environment International
Background: Phthalate exposure may contribute to hypertensive disorders of pregnancy (HDP), including preeclampsia/eclampsia (PE/E), but epidemiologic studies are lacking.
J. Meeker, Kristen L. McArthur, Jennifer A. Adibi, A. Alshawabkeh, Emily S. Barrett, Sara G. Brubaker, J. Cordero, D. Dabelea, A. Dunlop, J. Herbstman, Linda G. Kahn, C. Karr, Shilpi S. Mehta-Lee, Thomas G. O'Connor, S. Sathyanarayana, L. Trasande, J. Kuiper   +16 more
semanticscholar   +1 more source

Generative Artificial Intelligence Utilization and Perspectives Among Reproductive‐Age Women With Systemic Autoimmune and Rheumatic Diseases

Arthritis Care &Research, EarlyView.
Objective Reproductive‐age women with systemic autoimmune and rheumatic diseases (SARDs) have unique information needs related to their SARDs and reproductive health. We sought to understand their use of and receptivity to current and hypothetical generative artificial intelligence (AI) tools for health information‐seeking. Methods We conducted a cross‐
Mariam Arif, Catherine Wright, Samantha Rodriguez, Sarah Graves, Tamar Krishnamurti, Mehret Birru Talabi   +5 more
wiley   +1 more source

Impact of Skin Care Products on Phthalates and Phthalate Replacements in Children: the ECHO-FGS

Environmental Health Perspectives
Background: Phthalates and their replacements have been implicated as developmental toxicants. Young children may be exposed to phthalates/replacements when using skin care products (SCPs).
Michael S. Bloom, Juliana M. Clark, John L Pearce, Pamela L. Ferguson, Roger Newman, James R. Roberts, W. A. Grobman, Anthony C. Sciscione, D. Skupski, Kelly García, John E. Vena, K. Hunt   +11 more
semanticscholar   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Common atrium (fetal echo)

Radiopaedia.org, 2020
Mostafa El-Feky, Ahmed Esawy
semanticscholar   +1 more source