Results 71 to 80 of about 1,325,442 (244)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Robust Fetal Pose Estimation across Gestational Ages via Cross-Population Augmentation [PDF]

open access: yesInternational Conference on Medical Image Computing and Computer-Assisted Intervention
Fetal motion is a critical indicator of neurological development and intrauterine health, yet its quantification remains challenging, particularly at earlier gestational ages (GA).
Sebastian Diaz   +7 more
semanticscholar   +1 more source

Echo Cancellation - A Likelihood Ratio Test for Double-talk Versus Channel Change [PDF]

open access: yes, 2006
Echo cancellers are in wide use in both electrical (four wire to two wire mismatch) and acoustic (speaker-microphone coupling) applications. One of the main design problems is the control logic for adaptation.
Tourneret, Jean-Yves, Bershad, Neil J.
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

GESTATIONAL ECHO BIOMETRY IN BRACHYCEPHALIC PREGNANT BITCHES

open access: yesCiência Animal Brasileira, 2015
Ultrasonography is an accurate pregnancy diagnostic method, besides being completely innocuous for female and fetuses evaluation. The objective of this paper was to determine the reference values for gestational echo biometry of different breeds of ...
Marcus Antônio Rossi Feliciano   +5 more
doaj   +3 more sources

Fetal magnetic resonance imaging diagnosis of pulmonary lymphangiectasia in hypoplastic left heart syndrome: Association with fetal echocardiography and postnatal outcome

open access: yesJournal of Cardiovascular Magnetic Resonance
: Background: Secondary pulmonary lymphangiectasia (PL) is a recognised complication of hypoplastic left heart syndrome (HLHS) with an intact or restrictive atrial septum, associated with poor postnatal outcomes.
Greg Leonard   +14 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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