Results 31 to 40 of about 5,983,305 (250)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Role of Genes and Environment on Fetal Growth [PDF]

, 2014
Fetal growth is influenced by the in utero environment and genetic factors inherited from both parents. Poor fetal growth leading to low birth weight is associated with insulin resistance and type-2 diabetes in later life.
Hillman, SL
core  

Genetic and Environmental Influences on Fetal Growth Vary during Sensitive Periods in Pregnancy

Scientific Reports, 2018
Aberrant fetal growth is associated with morbidities and mortality during childhood and adult life. Although genetic and environmental factors are known to influence in utero growth, their relative contributions over pregnancy is unknown.
Tsegaselassie Workalemahu, Katherine L. Grantz, Jagteshwar Grewal, Cuilin Zhang, Germaine M. Buck Louis, Fasil Tekola-Ayele   +5 more
doaj   +1 more source

Associations of Longitudinal Fetal Growth Patterns With Cardiometabolic Factors at Birth

Frontiers in Endocrinology, 2021
BackgroundBirth weight is associated with cardiometabolic factors at birth. However, it is unclear when these associations occur in fetal life. We aimed to investigate the associations between fetal growth in different gestational periods and cord blood ...
Jia-Shuan Huang, Jia-Shuan Huang, Qiao-Zhu Chen, Si-Yu Zheng, Si-Yu Zheng, Rema Ramakrishnan, Ji-Yuan Zeng, Ji-Yuan Zeng, Can-Peng Zhuo, Can-Peng Zhuo, Yu-Mian Lai, Ya-Shu Kuang, Jin-Hua Lu, Jin-Hua Lu, Jian-Rong He, Jian-Rong He, Jian-Rong He, Xiu Qiu, Xiu Qiu   +18 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Fetal growth, early life circumstances, and risk of suicide in late adulthood.

, 2011
Recent studies in Sweden and Scotland have found early life conditions to be associated with increased risk of attempted and completed suicide in adolescence and young adulthood. It is not known, however, whether early life conditions affect suicide risk
Danziger, Phoebe Day, Silverwood, Richard, Koupil, Ilona, Danziger, P. D., Richard Silverwood, Ilona Koupil, Koupil, Ilona,, Phoebe Day Danziger, Silverwood, R.   +8 more
core   +1 more source

Maternal serum soluble fms-like tyrosine kinase-1–to–placental growth factor ratio distinguishes growth-restricted from non–growth-restricted small-for-gestational-age fetusesAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: Fetal growth restriction secondary to chronic placental insufficiency is a major cause of perinatal morbidity and mortality. A significant proportion of fetuses with fetal growth restriction are small for gestational age, defined as a ...
Prithi Rajiv, MD, Thomas Cade, MD, Jennifer Dean, MD, Gabriel Davis Jones, MD, Shaun P. Brennecke, MD, PhD   +4 more
doaj   +1 more source

Altered fetal growth, placental abnormalities, and stillbirth.

PLoS ONE, 2017
BackgroundWorldwide, stillbirth is one of the leading causes of death. Altered fetal growth and placental abnormalities are the strongest and most prevalent known risk factors for stillbirth.
Radek Bukowski, Nellie I Hansen, Halit Pinar, Marian Willinger, Uma M Reddy, Corette B Parker, Robert M Silver, Donald J Dudley, Barbara J Stoll, George R Saade, Matthew A Koch, Carol Hogue, Michael W Varner, Deborah L Conway, Donald Coustan, Robert L Goldenberg, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Stillbirth Collaborative Research Network (SCRN)   +16 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source