Results 151 to 160 of about 5,634,776 (298)

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

Glycosylated Fibronectin in Fetal Growth Restriction: An Emerging Biomarker of Placental Dysfunction. [PDF]

Cureus
Karoutsos DI, Stefanidis K, Michala L, Antsaklis P, Mavrogianni D, Asimakopoulos G, Daskalakis G.   +6 more
europepmc   +1 more source

Engineered Nanotopography to Modulate Growth and Signaling of Neuronal Networks

Advanced Functional Materials, EarlyView.
This study examines the interaction between neurons and nanoscale topographies on engineered substrates. Neurons cultured on nanowires, nanopillars and nanoneedles exhibit enhanced neurite outgrowth, form more organized neuronal circuits, and display improved synaptic connectivity, compared to flat substrates.
Hao Nguyen Tran, Kalyan Shobhana, Zlatan Trifunovic, Dan Smith, Michael Stuiber, Chennupati Jagadish, Mirella Dottori, Andrea J. O'Connor, Vini Gautam   +8 more
wiley   +1 more source

Factors Predicting Fetal Growth Restriction and Fetal Cardiac Remodeling

International Journal of General Medicine
XiaoLe Chen, Lili Xiao, Daozhu Wu, Saida Pan Department of Ultrasonic Diagnosis, the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of ChinaCorrespondence: Saida Pan ...
Chen X, Xiao L, Wu D, Pan S
doaj  

Brain sparing in fetal growth restriction: The double-edged sword of fetal hypoxaemia. [PDF]

J Physiol
Allison BJ, White TA, Camm EJ, Miller SL.   +3 more
europepmc   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Cardiac Function in Fetal Growth Restriction: A Systematic Review and Meta-Analysis. [PDF]

Prenat Diagn
D'Amico A, D'Antonio F, Della Valle L, Mappa I, Flacco ME, Manzoli L, Rizzo G, Prefumo F.   +7 more
europepmc   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Prognostic performance of umbilical artery Doppler-based classification in monochorionic pregnancies complicated by selective fetal growth restriction. [PDF]

Ultrasound Obstet Gynecol
Sorrenti S, Yaghi O, Prasad S, Mohammed D, Khalil A.   +4 more
europepmc   +1 more source

Restriction Of Fetal Growth

, 2017
Fetal growth restriction (RCF) is a clinical circumstance in which the fetus does not express its genetic potential for growth and as a final result a decrease in body weight occurs, which is below the 10th percentile for gestational age, in a selected growth curve. Among the etiological factors include: maternal, fetal and placental causes.
Ayala-Peralta, Félix, Ayala-Moreno, Dasio, Guevara-Ríos, Enrique, Luna-Figueroa, Antonio, Carranza-Asmat, César, Quiñones-Pereyra, Emma Ysabel, Ayala-Palomino, Richard, Quiñones-Vásquez, Luis Alberto, Sánchez-Góngora, Amadeo   +8 more
openaire   +1 more source