Barriers and facilitators of fetal heart monitoring with a mobile cardiotocograph (iCTG) device in underserved settings: An exploratory qualitative study from Tanzania. [PDF]
Mwakawanga DL+7 more
europepmc +1 more source
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen+8 more
wiley +1 more source
Automatic classification of fetal heart rate based on a multi-scale LSTM network. [PDF]
Rao L, Lu J, Wu HR, Zhao S, Lu BC, Li H.
europepmc +1 more source
An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment
Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su+12 more
wiley +1 more source
[Research on intelligent fetal heart monitoring model based on deep active learning]. [PDF]
Quan B+7 more
europepmc +1 more source
Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie+10 more
wiley +1 more source
Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu+15 more
wiley +1 more source
Evaluation of fetal cardiac morphology and function by fetal heart quantification technique in the normal second and third trimesters. [PDF]
Hu W+5 more
europepmc +1 more source
Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu+12 more
wiley +1 more source
Maternal Cocaine Administration During Pregnancy Induces Apoptosis in Fetal Rat Heart
Yuhui Xiao+3 more
openalex +1 more source