Results 291 to 300 of about 834,624 (377)

Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies. [PDF]

Stem Cell Res Ther
Chandraprabha PB, Azhagiri MKK, Venkatesan V, Magis W, Prasad K, Suresh S, Pai AA, Marepally S, Srivastava A, Mohankumar KM, Martin DIK, Thangavel S.   +11 more
europepmc   +1 more source

The Georgia type of nondeletional hereditary persistence of fetal hemoglobin has a C---T mutation at nucleotide-114 of the A gamma-globin gene [letter] [PDF]

, 1991
R Oner, F Kutlar, L-H. Gu, T. H. J. Huisman   +3 more
openalex   +1 more source

Isolation, Characterization, and Wound‐Healing Potential of β‐D‐Glucan from Lycoperdon pyriforme Schaeff

ChemistryOpen, EarlyView.
Mushrooms have become a prominent focus in alternative medicine and are now the subject of increasingly detailed scientific investigation. This study explores the isolation, purification, and characterization of β‐D‐glucan from Lycoperdon pyriforme, with particular emphasis on its wound‐healing potential. The aim of this research is to isolate, purify,
Elif Yavuz‐Dokgöz, Meltem Güleç, Burçin İzbudak, Onur Şahin, Ayça Bal‐Öztürk   +4 more
wiley   +1 more source

PGC-1α agonism induces fetal hemoglobin and exerts antisickling effects in sickle cell disease. [PDF]

Sci Adv
Sun Y, Benmhammed H, Al Abdullatif S, Habara A, Fu E, Brady J, Williams C, Ilinski A, Sharma A, Mahdaviani K, Alekseyev YO, Campbell JD, Steinberg MH, Cui S.   +13 more
europepmc   +1 more source

A systematic review of known mechanisms of hydroxyurea-induced fetal hemoglobin for treatment of sickle cell disease

Expert Review of Hematology, 2015
G. Pule, S. Mowla, N. Novitzky, C. Wiysonge, A. Wonkam   +4 more
semanticscholar   +1 more source

Studies on Yak Hemoglobin (Bos Grunniens, Bovidae) [PDF]

, 1985
Braunitzer, G., Lalthantluanga, R., Wiesner, Henning   +2 more
core  

Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation

ChemistryOpen, EarlyView.
The cyclodextrin polymer is conjugated with 35 deferoxamine units and can form iron(III) complexes. The polymer exhibits significantly lower antiproliferative activity than free deferoxamine. The cyclodextrin polymer with multiple deferoxamine units may present a promising strategy for improving the efficacy of iron chelation therapies.
Roberta Panebianco, Maurizio Viale, Graziella Vecchio   +2 more
wiley   +1 more source

Teratoid Hepatoblastoma: Clinicopathologic Features and Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Teratoid hepatoblastoma (HB) is a rare histologic subtype of the most common pediatric liver cancer. Understanding of the clinicopathologic features and outcomes of patients with this disease is currently limited. Methods Multi‐institution, retrospective chart review was conducted to compare 20 children with teratoid HB to 129 ...
Brian T. Hickner, Andres F. Espinoza, Soo Jin Cho, Stephen Sarabia, Martin Urbicain, Ann Wang, Sanjeev A. Vasudevan, Dolores H. López‐Terrada, Kalyani R. Patel   +8 more
wiley   +1 more source

Upregulation of miR‑6747‑3p affects red blood cell lineage development and induces fetal hemoglobin expression by targeting BCL11A in β‑thalassemia. [PDF]

Mol Med Rep
Lv A, Chen M, Zhang S, Zhao W, Li J, Lin S, Zheng Y, Lin N, Xu L, Huang H.   +9 more
europepmc   +1 more source

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

Cell, 2018
Nan Liu, Victoria V. Hargreaves, Qian Zhu, Jesse V. Kurland, Jiyoung A. Hong, Woojin Kim, F. Sher, Claudio Macias-Treviño, J. Rogers, R. Kurita, Yukio Nakamura, Guocheng Yuan, D. E. Bauer, Jian Xu, M. Bulyk, S. Orkin   +15 more
semanticscholar   +1 more source