Results 61 to 70 of about 38,189 (304)

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Gradual diagnosis and clinical importance of prenatally detected persistent left superior vena cava with absent right superior vena cava – a case report and literature review

Journal of Ultrasonography, 2020
Persistent left superior vena cava is a malformation of cardinal veins. We report a case of a secundigravida who had many fetal ultrasound examinations – first performed by an obstetrician (who described fetal mediastinum as “abnormal”), second by other ...
Sylwestrzak Oskar, Respondek-Liberska Maria   +1 more
doaj   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Clinical Significance of Abnormalities in Fetal Kidney Location or Number Diagnosed by Prenatal Ultrasound

Clinical and Experimental Obstetrics & Gynecology
Background: The abnormal position or number of fetal kidneys accounts for 15%–20% of congenital abnormalities in the fetus, often resulting in oligo amniotic fluid or no amniotic fluid, thus affecting the development of fetal lung and ...
Lihong He, Jing Zhao, Hongli Wang, Rong Wei, Yun Liu, Xiaoxia Zha, Chunguo Zhang   +6 more
doaj   +1 more source

Small‐for‐gestational‐age fetus diagnosed in the second trimester: Possible etiologies and short‐term neonatal outcomes

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction The aim of our study was to investigate the causes of fetal growth
Lucia Pasquini, Giulia Masini, Greta Cagninelli, Teresa Polimeno, Nicola Fratelli, Anna Fichera, Federico Prefumo   +6 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Human cytomegalovirus (CMV) dysregulates neurodevelopmental pathways in cerebral organoids

Communications Biology
Human cytomegalovirus (CMV) infection is the leading non-genetic aetiology of congenital malformation in developed countries, causing significant fetal neurological injury.
Ece Egilmezer, Stuart T. Hamilton, Charles S. P. Foster, Manfred Marschall, William D. Rawlinson   +4 more
doaj   +1 more source

Pregnancy and Epilepsy: Clinical Data and Adverse Outcomes of Pregnant Women with Epilepsy

Archives of Epilepsy, 2021
Objectives:Pregnancy in women with epilepsy carries a higher risk for fetal development complications, including congenital malformations. In this study, data obtained from pregnant epilepsy patients in a tertiary epilepsy center were presented.Methods ...
Zeynep BASTUG GUL, Gunay GUL, Fulya EREN, Sena AKSOY, Ayten CEYHAN DIRICAN, Butül TEKIN, Dilek ATAKLI   +6 more
doaj   +1 more source

Imaging of vein of Galen malformation in late trimester: Fetal MRI

, 2022
Vein of Galen malformation is a rare congenital vascular malformation due to the maldevelopment of the embryonic precursor median vein of Markowski. It results in significant morbidity and mortality in a fetus and neonate.
Regmi, Pradeep Raj, Amatya, Isha
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