Results 41 to 50 of about 956,605 (274)

Comparison of LPS-stimulated release of cytokines in punch versus transwell tissue culture systems of human gestational membranes [PDF]

, 2010
Background Cytokine signaling within the amnionic, chorionic and decidual extraplacental gestational membranes plays an important role in membrane rupture and the timing of birth.
Loch-Caruso, Rita, Miller, Mark F.
core   +4 more sources

Functional Genomics of Healthy and Pathological Fetal Membranes

Frontiers in Physiology, 2020
Premature preterm rupture of membranes (PPROM), rupture of fetal membranes before 37 weeks of gestation, is the leading identifiable cause of spontaneous preterm births.
Sarah J. Cunningham, Sarah J. Cunningham, Sarah J. Cunningham, Sarah J. Cunningham, Liping Feng, Terrence K. Allen, Timothy E. Reddy, Timothy E. Reddy, Timothy E. Reddy, Timothy E. Reddy   +9 more
doaj   +1 more source

The endogenous production of hydrogen sulphide in intrauterine tissues [PDF]

, 2009
Background: Hydrogen sulphide is a gas signalling molecule which is produced endogenously from L-cysteine via the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE).
Carson, Ray J., Heptinstall, John, Patel, Pushpa, Vatish, Manu, Wang, Rui   +4 more
core   +5 more sources

Placental syncytiotrophoblast constitutes a major barrier to vertical transmission of Listeria monocytogenes. [PDF]

, 2010
Listeria monocytogenes is an important cause of maternal-fetal infections and serves as a model organism to study these important but poorly understood events. L.
A Beham, A Le Monnier, A Moffett, A Shen, AI Bakardjiev, AI Bakardjiev, AI Bakardjiev, AJ Teberg, AM Carter, Anna I. Bakardjiev, AV Lallemand, B Swaminathan, BF King, C Coutifaris, C Floridon, C Kocks, C Sundstrom, CA Kirkbride, CD Ockleford, DA Drevets, DA Drevets, DA Portnoy, DA Portnoy, David S. Schneider, DK Bishop, E Maidji, E Mylonakis, EG Pamer, G Scheuner, H Bierne, H Koi, HM Cobe, IJ Glomski, J Mengaud, J Skoble, J Trowsdale, JA Theriot, Jennifer R. Robbins, JR Robbins, K Benirschke, K Red-Horse, K Red-Horse, Kasia M. Skrzypczynska, KS Kim, L Forner, L Vicovac, LG Tilney, LM Brown, M Berryman, M Lecuit, M Lecuit, M Lecuit, M O'Riordan, M Pentecost, Mirhan Kapidzic, NM Hunkapiller, O Disson, O Genbacev, O Genbacev, O Genbacev, P Cossart, PB Medawar, PD Barnes, PM Drake, RK Miller, RL Goldenberg, S Fisher, S Jones, S Kaur, S Notermans, SJ Cantle, SJ Fisher, SJ Fisher, SR Sooranna, T Kajii, T Rajabian, T Wollert, TH Schiebler, Varvara B. Zeldovich, Y Huang, Y Shen, Y Zhou, Z Vacek   +82 more
core   +3 more sources

Programmed Fetal Membrane Senescence and Exosome-Mediated Signaling: A Mechanism Associated With Timing of Human Parturition

Frontiers in Endocrinology, 2017
Human parturition is an inflammatory process that involves both fetal and maternal compartments. The precise immune cell interactions have not been well delineated in human uterine tissues during parturition, but insights into human labor initiation have
Ramkumar Menon, Sam Mesiano, Robert N. Taylor   +2 more
doaj   +1 more source

Phase transitions in single neurons and neural populations: Critical slowing, anesthesia, and sleep cycles [PDF]

, 2010
The firing of an action potential by a biological neuron represents a dramatic transition from small-scale linear stochastics (subthreshold voltage fluctuations) to gross-scale nonlinear dynamics (birth of a 1-ms voltage spike). In populations of neurons
Sleigh, James W., Steyn-Ross, D. Alistair, Steyn-Ross, Moira L., Wilson, Marcus T.   +3 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes [PDF]

, 2015
Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition.
Aardema, Alves, Arsic, Asselin, Carluccio, Catov, Challis, Chen, Cheng, Cheng, Cheng, Cheng, Cherny, Chu, Crane, D.C. Wathes, D.R.E. Abayasekara, Flynn, Goncalves, Guillou, Herath, Jabbour, Karsch, Kim, Klein, Lamont, Lee, Leung, Lewis, Lunn, M. Elmes, Nielsen, Noble, Poyser, Reddy, Rimoldi, Robinson, S. Kirkup, Sharp, Smith, Smith, Thorburn, Villa, Wang, Wathes, Wendell, Whittle, Witkin, Z. Cheng, Zhang   +49 more
core   +2 more sources

Healing of Preterm Ruptured Fetal Membranes [PDF]

Scientific Reports, 2017
AbstractPreterm premature rupture of membrane (pPROM) is associated with 30–40% of preterm births. Infection is considered a leading cause of pPROM due to increased levels of proinflammatory cytokines in amniotic fluid. Only 30%, however, are positive for microbial organisms by amniotic fluid culture.
Mogami, Haruta, Hari Kishore, Annavarapu, Akgul, Yucel, Word, R. Ann   +3 more
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source