Results 131 to 140 of about 39,128 (299)

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

The Relationship between Umbilical Artery PH and Maternal Risk Factors in Premature Birth

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: In many deliveries, determination of umbilical artery PH is considered a suitable tool for predicting the risk of damage to the fetus and determining the likelihood of associated complications. This study was performed in ...
Z Akbarian, M Haghshenas, K Hajian, N Asnafi, V Hajaliakbar   +4 more
doaj  

بررسی اثر آنتی‌بيوتيک درمانی در پارگی زودرس پيش از ترم کيسه آب [PDF]

, 2006
زمينه و هدف: از آنجا که مطالعات انجام شده در مورد تاثير و لزوم تجويز آنتی‌بيوتيک در حاملگی‌های با پارگی زودرس کيسه آب قبل از ترم هنوز به پاسخ روشن نرسيده‌اند، اين مطالعه با هدف بررسی اثر آنتی‌بيوتيک در طولانی کردن فاز تاخيری زايمان و اثر آن بر بهبود ...
بهاءصدری, شهره, ناطقی, کیوان   +1 more
core  

Evolving Features of RASopathies Among Pregnancies With Abnormal Fetal Fluid Collections

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective We aimed to characterize the fetal features across gestation and describe genotype‐phenotype correlations for pregnancies with fetal RASopathies that were more severely affected as they presented with at least one abnormal fluid collection.
Natalie B. Gulrajani, John Boscardin, Billie R. Lianoglou, Katie Tick, Carmen M. A. Santoli, Kristen A. Miller, Angie C. Jelin, Lorraine Dugoff, Rose Giardine, Cori Feist, Rachel Pilliod, Stephanie Dukhovny, Kelly Gilmore, Neeta L. Vora, Aisling Murphy, Peter N. Robinson, Mary E. Norton, Teresa N. Sparks   +17 more
wiley   +1 more source

Intrauterine Transfusions in Fetuses Affected by Parvovirus B19: Complications, Challenges and Outcomes

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir, Emma Van den Eede, Lone N. Nørgaard, Roland Devlieger, Karin Sundberg, Monique C. Haak, Femke Slaghekke   +6 more
wiley   +1 more source

Effect of Targeted Aspirin Administration Based on First Trimester Combined Screening for Preeclampsia on Preterm Birth: An Interrupted Time Series Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objectives To assess the effect of an aspirin intervention program on preterm birth (PTB) rates in women identified as high‐risk for preterm preeclampsia in the first‐trimester screening. Design This is a retrospective study evaluating the impact of the intervention program on preterm birth using interrupted time series analysis (ITSA) with an
Monica Minopoli, Alicia Martínez‐Varea, Claire Pegorie, Pilar Palmrich, Ana Pinas, Basky Thilaganathan   +5 more
wiley   +1 more source

Clinical Characteristics Associated With Very Preterm Delivery Despite Transabdominal Cerclage: A Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To identify factors associated with unsuccessful transabdominal cerclage (TAC) insertion, defined as delivery before 32 weeks, including maternal demographics, preterm birth risk factors, operative details (laparoscopic or open, pre‐pregnancy or during pregnancy) and subsequent cervical length.
Laura van der Krogt, Lisa Story, Natalie Suff, Andrew Shennan   +3 more
wiley   +1 more source

Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika, Meletios P. Nigdelis, Angelos Daniilidis, Erich‐Franz Solomayer, Irene Lambrinoudaki, Efstratios M. Kolibianakis, Dimitrios G. Goulis   +6 more
wiley   +1 more source