Results 241 to 250 of about 389,526 (301)

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

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Fetal membrane dynamics

American Journal of Obstetrics and Gynecology, 1976
The validity of the concepts of exchange and net flow and of the method used to measure them was proved by utilizing a standard artificial membrane. The exchange rates across the amniochorion of D- and L-isomers of various amino acids have been measured. They do not differ.
openaire   +2 more sources

Premature Rupture of Fetal Membranes

Postgraduate Medicine, 1967
Premature rupture of fetal membranes increases maternal morbidity and perinatal mortality when labor does not ensue promptly. Two schools of management of this problem have developed: the activists, who favor induction of labor if it does not occur spontaneously within 24 hours, and the conservatives, who prefer close clinical observation with no ...
J, Rivkind, B J, Pisani
openaire   +2 more sources

Intact fetal membranes

Acta Obstetricia et Gynecologica Scandinavica, 1983
Abstract. Samples from different parts of the fetal membranes were examined by both light and transmission electron microscopy. Samples were obtained during elective ce‐sarean section after full‐term normal pregnancy. The results indicated that the different layers of the membranes had undergone ukrastructural changes varying according to the site ...
M E, Ibrahim, M N, Bou-Resli, N S, Al-Zaid, L F, Bishay   +3 more
openaire   +2 more sources

BULK FLOWS THROUGH HUMAN FETAL MEMBRANES

Obstetrical & Gynecological Survey, 1976
Bulk water flows across term human amnio-chorion are studied <i>in vitro. </i>The hydrodynamic permeability is found to vary with both hydrostatic and osmotic pressure. The coefficient characterizing flows generated by hydrostatic pressure is substantially larger than that characterizing osmotic flows.
D R, Abramovich, K R, Page, L, Jandial
openaire   +2 more sources

The Placenta and Fetal Membranes

The American Journal of the Medical Sciences, 1960
to the very rapidly expanding list of available texts, reviews, and symposia dealing with medical and basic scientific topics. Basically, this work presents the proceedings of a conference dealing with the placenta and fetal membranes. This conference, sponsored by the Association for the Aid of Crippled Children, was held in November, 1958, at ...
openaire   +2 more sources

[Biomechanical characteristics of human fetal membranes. Preterm fetal membranes are stronger than term fetal membranes].

Gynecologie, obstetrique & fertilite, 2011
The purpose of this study was to determine the biomechanical characteristics of human fetal membranes (FM) throughout gestation. Biomechanical properties were determined for 115 FM of 23-41 weeks gestation using our previously described methodology. The areas of membrane immediately adjacent to the strongest and weakest tested spots were sampled for ...
N, Rangaswamy, A, Abdelrahim, R M, Moore, L, Uyen, B M, Mercer, J M, Mansour, D, Kumar, J, Sawady, J J, Moore   +8 more
openaire   +1 more source

Histopathology of retained bovine fetal membranes

Theriogenology, 1994
Placentomes were obtained from 20 cows with retained placenta (9 following normal birth, 5 after abortion and 6 with dystocia), and this material was examined by light microscopy. Histologic changes that were consistently seen in placentomes of cows with retained placenta after normal birth included vascular changes (edema, thrombosis and vasculitis ...
H I, Al-Sadi, A F, Majeed, A M, Ridha
openaire   +2 more sources