Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Value of Non-Invasive Fetal Monitoring Techniques in Detection of Fetal Metabolic Acidemia at Birth
Objective. Purpose of the study was to evaluate the diagnostic accuracy of fetal pulse oximetry (FPO) and STanalysis of the fetal ECG (STAN) in prediction of fetal acidemia at birth. Methods.
Dokus K+4 more
doaj +1 more source
Intrapartum Fetal Heart Rate: A Possible Predictor of Neonatal Acidemia and APGAR Score
Background: Predicting perinatal outcomes based on patterns of fetal heart rate (FHR) remains a challenge. The aim of this study was to evaluate intrapartum FHR variability as predictor for neonatal acidemia and APGAR score.Methods: This was a ...
Thâmila Kamila de Souza Medeiros+9 more
doaj +1 more source
New Method for Beat-to-Beat Fetal Heart Rate Measurement Using Doppler Ultrasound Signal
The most commonly used method of fetal monitoring is based on heart activity analysis. Computer-aided fetal monitoring system enables extraction of clinically important information hidden for visual interpretation—the instantaneous fetal heart rate (FHR)
Tomasz Kupka+7 more
doaj +1 more source
The Fourier Evaluation of Tracings and Acidosis in Labor: the FETAL Technique [PDF]
Adequate fetal and neonatal development depend upon the presence of a normal acid-base environment during pregnancy and the smooth transition from intra-uterine to extra-uterine life. Current methods to assess fetal pH and acid-base status are invasive and carry significant maternal and fetal risks.
arxiv
An Improved Model Ensembled of Different Hyper-parameter Tuned Machine Learning Algorithms for Fetal Health Prediction [PDF]
Fetal health is a critical concern during pregnancy as it can impact the well-being of both the mother and the baby. Regular monitoring and timely interventions are necessary to ensure the best possible outcomes. While there are various methods to monitor fetal health in the mother's womb, the use of artificial intelligence (AI) can improve the ...
arxiv
Intelligent Structured Intermittent Auscultation (ISIA): Evaluation of a decision-making framework for fetal heart monitoring of low-risk women [PDF]
Background: Research-informed fetal monitoring guidelines recommend intermittent auscultation (IA) for fetal heart monitoring for low-risk women. However, the use of cardiotocography (CTG) continues to dominate many institutional maternity settings ...
Foureur, MJ, Maude, RM, Skinner, JP
core +1 more source
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Feasibility of a fetal measurement electrode system [PDF]
Findings of the study are summarized and conclude that all monitoring requirements are not currently satisfied. An approach is presented to provide a multiparametric monitoring system through combinations of existing transducers.
core +1 more source
To compare intrapartum cardiotocographic (CTG) recording with conventional intermittent fetal heart auscultation during labor [PDF]
Standard evaluation of fetal well-being during labor includes the periodic assessment of the fetal heart rate (FHR), its pattern and response to intrapartum stimuli and events.
Bansal, Isha+5 more
core +2 more sources