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Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche +8 more
wiley +1 more source
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Obstetrics & Gynecology, 2009
In 2008, the Eunice Kennedy Shriver National Institute of Child Health and Human Development published guidelines for categorizing fetal heart rate patterns. However, even if universally adopted, they will fail to improve outcomes unless they are integrated into a "bundle" of activities.
Howard, Minkoff, Richard, Berkowitz
openaire +2 more sources
In 2008, the Eunice Kennedy Shriver National Institute of Child Health and Human Development published guidelines for categorizing fetal heart rate patterns. However, even if universally adopted, they will fail to improve outcomes unless they are integrated into a "bundle" of activities.
Howard, Minkoff, Richard, Berkowitz
openaire +2 more sources
Journal of Biomedical Engineering, 1988
This paper introduces fetal monitoring by describing the medical problems of the fetus in utero. The various methods currently used to monitor the fetus are reviewed with their respective advantages and shortcomings. New methods of surveillance of the fetus are highlighted as well as the mother's reaction to the technology.
openaire +3 more sources
This paper introduces fetal monitoring by describing the medical problems of the fetus in utero. The various methods currently used to monitor the fetus are reviewed with their respective advantages and shortcomings. New methods of surveillance of the fetus are highlighted as well as the mother's reaction to the technology.
openaire +3 more sources
JAMA: The Journal of the American Medical Association, 1981
To the Editor.— We are writing in reference to the SPECIAL COMMUNICATION, "Impact of Electronic Fetal Monitoring on Obstetric Management" by Orvan W. Hess, MD (1980;244:682). Dr Hess' review is incomplete and biased, as well as inaccurate in some instances, recurrently demonstrating his position as an advocate of universal electronic fetal monitoring (
H D, Banta, S B, Thacker
openaire +2 more sources
To the Editor.— We are writing in reference to the SPECIAL COMMUNICATION, "Impact of Electronic Fetal Monitoring on Obstetric Management" by Orvan W. Hess, MD (1980;244:682). Dr Hess' review is incomplete and biased, as well as inaccurate in some instances, recurrently demonstrating his position as an advocate of universal electronic fetal monitoring (
H D, Banta, S B, Thacker
openaire +2 more sources

