Results 61 to 70 of about 4,947,559 (270)

Effect of social support on fetal movement self-monitoring behavior in Chinese women: a moderated mediation model of health beliefs

Journal of Psychosomatic Obstetrics and Gynecology
Objective Strengthening the management of women’s self-monitoring during pregnancy is important to reduce fetal death in utero and improve maternal and infant outcomes.
Changmin Niu, Yue Xie, Wangxuan Zhou, Yue Ren, Ying Zheng, Lin Li   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Sensors for Fetal Hypoxia and Metabolic Acidosis: A Review

Sensors, 2018
This article reviews existing clinical practices and sensor research undertaken to monitor fetal well-being during labour. Current clinical practices that include fetal heart rate monitoring and fetal scalp blood sampling are shown to be either ...
Gerard Cummins, Jessica Kremer, Anne Bernassau, Andrew Brown, Helen L. Bridle, Holger Schulze, Till T. Bachmann, Michael Crichton, Fiona C. Denison, Marc P. Y. Desmulliez   +9 more
doaj   +1 more source

Fetal heart rate monitoring practices at a public hospital in Northern Uganda – what health workers document, do and say

Global Health Action, 2020
Background: In Uganda, perinatal mortality is 38 per 1000 pregnancies. One-third of these deaths are due to birth asphyxia. Adequate fetal heart rate (FHR) monitoring during labor may detect birth asphyxia but little is known about monitoring practices ...
Elizabeth Ayebare, Wibke Jonas, Grace Ndeezi, Jolly Nankunda, Claudia Hanson, James K. Tumwine, Anna Hjelmstedt   +6 more
doaj   +1 more source

Professionals' views of fetal-monitoring support the development of devices to provide objective longer-term assessment of fetal wellbeing

Journal of Maternal-Fetal & Neonatal Medicine, 2016
Objective: Continuous longer-term fetal monitoring has been proposed to address limitations of current technologies in the detection of fetal compromise.
Rebecca Brown, E. Johnstone, A. Heazell
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Atrioventricular conduction abnormalities are associated with poor outcome following intermittent umbilical cord occlusions in fetal sheep

Acta Obstetricia et Gynecologica Scandinavica
Introduction Fetal arrhythmias have been described with intrapartum hypoxemia; however, they cannot be accurately diagnosed with currently used fetal heart rate (FHR) monitoring systems due to low resolution and signal averaging.
Juulia Lantto, Jonas Johnson, Heikki Huhta, Mervi Haapsamo, Panu Kiviranta, Kati Räsänen, Hanna‐Marja Voipio, Sven‐Erik Sonesson, Juha Voipio, Juha Räsänen, Ganesh Acharya   +10 more
doaj   +1 more source

Doppler Ultrasound Technology for Fetal Heart Rate Monitoring: A Review

IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2020
Fetal well-being is commonly assessed by monitoring the fetal heart rate (fHR). In clinical practice, the de facto standard technology for fHR monitoring is based on the Doppler ultrasound (US). Continuous monitoring of the fHR before and during labor is
Paul Hamelmann, R. Vullings, Alexander F. Kolen, J. Bergmans, J. V. van Laar, P. Tortoli, M. Mischi   +6 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Assessing signal loss, accuracy, and acceptability of an ambulatory fetal electrocardiography with cardiotocography in the antepartum and intrapartum phases

Acta Obstetricia et Gynecologica Scandinavica
Introduction Electronic fetal heart rate (FHR) monitoring is integral to antepartum and intrapartum care to detect fetal compromise, reducing neonatal morbidity and mortality. Conventional wired cardiotocography (CTG) limits mobility, birthing positions,
Marie Min Tse Tan, Kirsten Jie Ying Ong, Michelle Mei Ying Tiong, Rehena Sultana, Chuyen Luong, Serene Thain, Devendra Kanagalingam, Jerry Kok Yen Chan, See Ling Loy, Chee Wai Ku   +9 more
doaj   +1 more source