Results 41 to 50 of about 1,852,080 (263)

Spatial patterns of avoidable fetal mortality and social deprivation [PDF]

open access: yesRevista Brasileira de Epidemiologia
: Objective: To develop a social need index for stratification of municipalities and identification of priority areas for reducing fetal mortality. Methods: ecological study, carried out in the state of Pernambuco, between 2010 and 2017.
Indianara Maria de Barros Canuto   +6 more
doaj   +3 more sources

Towards a Global Understanding of Tree Mortality [PDF]

open access: yes
Rates of tree mortality are increasing globally, with implications for forests and climate. Yet, how and why these trends vary globally remain unknown. Developing a comprehensive assessment of global tree mortality will require systematically integrating
Senf, Cornelius   +2 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Cumulative incidence of lethal congenital anomalies in Peru

open access: yesRevista de la Facultad de Medicina, 2020
Introduction: Lethal congenital anomalies (LCA) are anomalies associated with early stillbirth or newborn death. Currently, there are no data on the incidence of LCAs in Peru.
Alvaro Taype-Rondan   +3 more
doaj   +1 more source

Maternal Cardiovascular Impairment in Pregnancies Complicated by Severe Fetal Growth Restriction [PDF]

open access: yes, 2012
—Fetal growth restriction and preeclampsia are both conditions of placental etiology and associated to increased risk for the long-term development of cardiovascular disease in the mother. At presentation, preeclampsia is associated with maternal global
Thilaganathan, B   +3 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Reexamining the effects of gestational age, fetal growth, and maternal smoking on neonatal mortality

open access: yesBMC Pregnancy and Childbirth, 2004
Background Low birth weight (
Platt Robert W, Ananth Cande V
doaj   +1 more source

Outcome of Pregnancy in Women With D‐Transposition of the Great Arteries: A Systematic Review

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Information on maternal and fetal outcomes of pregnancy in women with D‐transposition of the great arteries is limited. We conducted a systematic literature review on pregnancies in women with transposition of the great arteries after atrial ...
Jena Pizula   +8 more
doaj   +1 more source

The effects of designation and volume of neonatal care on mortality and morbidity outcomes of very preterm infants in England : retrospective population-based cohort study [PDF]

open access: yes, 2014
Objective: To examine the effects of designation and volume of neonatal care at the hospital of birth on mortality and morbidity outcomes in very preterm infants in a managed clinical network setting.
Draper, E S   +27 more
core   +1 more source

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