Results 81 to 90 of about 3,047,819 (288)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Propuesta de un certificado de defunción para mejorar el registro y reporte de la muerte en el periodo perinatal Proposal for a death certificate to improve recording and reporting of perinatal mortality

Salud Pública de México, 2001
Objetivo. Analizar la forma en que se registran los nacimientos y la muerte en el periodo perinatal, en el Instituto Mexicano del Seguro Social (IMSS), y documentar si el registro de la muerte, en este periodo, es adecuado. Material y métodos.
Javier Contreras-Lemus, Samuel Flores-Huerta, Jorge Arturo Cardona-Pérez   +2 more
doaj  

The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight

PLoS Medicine, 2017
Background Perinatal mortality and morbidity continue to be major global health challenges strongly associated with prematurity and reduced fetal growth, an issue of further interest given the mounting evidence that fetal growth in general is linked to ...
T. Kiserud, T. Kiserud, G. Piaggio, G. Carroli, M. Widmer, J. Carvalho, L. Jensen, D. Giordano, J. Cecatti, H. Aleem, Sameera A Talegawkar, A. Benachi, A. Diemert, Antoinette Tshefu Kitoto, J. Thinkhamrop, P. Lumbiganon, A. Tabor, A. Kriplani, Rogelio González Perez, K. Hecher, M. Hanson, A. M. Gülmezoglu, L. Platt   +22 more
semanticscholar   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

[Risk factors for fetal mortality in a public maternity hospital in Rio de Janeiro, Brazil: a case-control study].

Cadernos de Saúde Pública, 2010
Stillbirth rate is high in Brazil, and it is important to identify its determinants. A nested case-control was conducted to explore the determinants of fetal death in a population treated at public services in Rio de Janeiro from 2002 to 2004.
S. Fonseca, E. Coutinho
semanticscholar   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

One‐Step Curcumin‐Mediated Multiphoton Lithography for Bioactive 3D Scaffolds

Advanced Functional Materials, EarlyView.
Curcumin‐mediated multiphoton lithography enables one‐step fabrication of highly architected complex gelatin methacryloyl scaffolds by exploiting curcumin as a multifunctional bioactive photoinitiator. The resulting 3D structures support mesenchymal stem cell adhesion, proliferation, and migration, while exhibiting dual antibacterial activity through ...
Myrto Charitaki, Michalis Stavrou, Chrysanthi Pinelopi Apostolidou, Elmina Kabouraki, David Gray, Anna Mitraki, Anthi Ranella, Maria Farsari   +7 more
wiley   +1 more source

MORTALIDAD PERINATAL HOSPITALARIA EN EL PERÚ: FACTORES DE RIESGO

Revista Chilena de Obstetricia y Ginecología, 2005
Objetivo: Identificar los factores de riesgo de la mortalidad perinatal hospitalaria en el Perú y determinar su valor predictivo. Material y Método: Estudio de casos y controles, utilizando información del Sistema Informático Perinatal de 9 hospitales ...
Manuel Ticona R., Diana Huanco A.
doaj