Results 21 to 30 of about 329,411 (267)

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source

An evaluation of antenatal corticosteroid use and timing in a large US birth cohort 2017–2021

Pregnancy
Introduction There is a lack of published data on the contemporary use and timing of antenatal corticosteroids in the United States. Our primary objective was to address this gap using clinical data from a large US birth cohort.
Vivienne Souter, C. Andrew Combs, Ian Painter, Kristin Sitcov, Lisa Foglia, Sarah M. Edwards, Asma Khalil, Andreas Hoehn   +7 more
doaj   +1 more source

Fetal Arrhythmias and Related Fetal and Neonatal Outcomes [PDF]

International Journal of Women's Health and Reproduction Sciences, 2015
Fetal cardiac arrhythmia has good prognosis. However, some can lead to hydrops fetalis and perinatal mortality. There are not sufficient studies on the prevalence and complications of fetal arrhythmias in Iran, thus, making parents anxious. Therefore, we performed this study to determine its proper management and to prevent its complications during ...
Fatemeh Abbasalizadeh, Shamsi Abbasalizadeh, Shamsi Ghaffari, Rabee Hesami, Leyla Hesmai   +4 more
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Pre-pregnancy body mass index and neonatal body weight in Japanese women with gestational diabetes mellitus: Hamamatsu GRACE Study 1

Endocrine Journal
Gestational diabetes mellitus (GDM) is closely associated with adverse fetal outcomes. Maternal underweight is associated with low birth weight (LBW) and small for gestational age (SGA).
Kei Takeshita, Takuya Hashimoto, Yukino Toyama, Ayumi Kanamoto, Teruki Miyake, Shinya Furukawa, Daisuke Tsuriya   +6 more
doaj   +1 more source

Fetal megacystis: prediction of spontaneous resolution and outcome [PDF]

Ultrasound in Obstetrics & Gynecology, 2017
AbstractObjectivesTo investigate the natural history of fetal megacystis from diagnosis in utero to postnatal outcome, and to identify prognostic indicators of spontaneous resolution and postnatal outcome after resolution.MethodsThis was a national retrospective cohort study. Fetal megacystis was defined in the first trimester as a longitudinal bladder
F. Fontanella, L. Duin, P. N. Adama van Scheltema, T. E. Cohen‐Overbeek, E. Pajkrt, M. Bekker, C. Willekes, C. J. Bax, C. M. Bilardo   +8 more
openaire   +6 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Congenital uterine anomalies and perinatal outcomes: a retrospective single-center cohort study

Clinical and Experimental Obstetrics & Gynecology, 2021
Congenital uterine anomalies result from the abnormal differentiation, migration, fusion and canalization of Mullerian ducts with a prevalence of 1-10% for unselected population, 2-8% for infertile women and 5-30% for women with a history of miscarriage.
Elisa Zambrotta, Luisa Maria Di Gregorio, Federica Di Guardo, Roberta Agliozzo, Giuliana Chiara Maugeri, Ferdinando Antonio Gulino, Silvia Cutello, Maria Cecilia Cerana, Marco Palumbo   +8 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source