Results 21 to 30 of about 256,689 (250)

Role of palliative care in centers performing maternal–fetal interventions

Frontiers in Pediatrics, 2023
Advancements in maternal–fetal interventions have allowed for direct fetal access, shifting the focus of interventions from maternal health for fetal health to a focus on sole fetal/neonatal benefit.
Erin Rholl, Erin Rholl, Steven R. Leuthner, Steven R. Leuthner   +3 more
doaj   +1 more source

CD200-CD200R imbalance correlates with microglia and pro-inflammatory activation in rat spinal cords exposed to amniotic fluid in retinoic acid-induced spina bifida

Scientific Reports, 2018
Spina bifida aperta is a congenital malformation characterized by the failure of neural tube closure resulting in an unprotected fetal spinal cord. The spinal cord then undergoes progressive damage, likely due to chemical and mechanical factors related ...
Marc Oria, Rebeca L. Figueira, Federico Scorletti, Lourenco Sbragia, Kathryn Owens, Zhen Li, Bedika Pathak, Maria U. Corona, Mario Marotta, Jose L. Encinas, Jose L. Peiro   +10 more
doaj   +1 more source

Fetal surgery

American Journal of Obstetrics and Gynecology, 1996
While most prenatally diagnosed malformations are best managed by appropriate medical and surgical therapy after birth, a few may require or benefit from correction before birth. Extensive experimental work in animals and innovative technologic developments have made fetal surgery a viable approach to perinatal care. Managing preterm labor continues to
openaire   +4 more sources

Peripartum Ultrasound-Guided Drainage of Cystic Fetal Sacrococcygeal Teratoma for the Prevention of the Labor Dystocia: A Report of Two Cases

American Journal of Perinatology Reports, 2011
Fetal sacrococcygeal teratoma (SCT) is the most common tumor in the neonatal period and is easily detected by modern ultrasound techniques, mostly during the second-trimester screening.
Vedran Stefanovic, Erja Halmesmäki
doaj   +1 more source

Pseudomeningocele after in utero repair of myelomeningocele as an early sign of hypertensive hydrocephalus – a case report and review of the literature

Archives of Pediatric Neurosurgery, 2021
Background Myelomenigocele (MMC) is the most common congenital defect of the spine. The Management of Myelomeningocele study (MOMS trial) demonstrated that the prenatal repair decreased shunt implant, reversal of hindbrain herniation and better ...
Daniel Dante Cardeal, Ingrid Schwach Werneck Britto, Sandra Rejane Silva Herbst, Milton Hikaru Toita, Gabriela Duarte Bordini, José Carlos Esteves Veiga, Rodrigo Ruano   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Quantifying prenatal and postnatal mortality in extreme early onset fetal growth restriction: A systematic review and incidence analysis

Pregnancy
Background and Objective Extreme early‐onset fetal growth restriction (EE‐FGR) is associated with significant perinatal morbidity and mortality. As short‐ and long‐term prognoses are influenced by both gestational age and severity of FGR, quantifying ...
Shohra Qaderi, Giulia Bonanni, Mohammadamin Parsaei, Ehsan Rojhani, Satjeet Deol Chauhan, Eyal Krispin, Dario O. Fauza, Anna L. David, Kjersti Aagaard, Alireza A. Shamshirsaz   +9 more
doaj   +1 more source

Placental Vessel Segmentation Using Pix2pix Compared to U-Net

Journal of Imaging, 2023
Computer-assisted technologies have made significant progress in fetoscopic laser surgery, including placental vessel segmentation. However, the intra- and inter-procedure variabilities in the state-of-the-art segmentation methods remain a significant ...
Anouk van der Schot, Esther Sikkel, Marèll Niekolaas, Marc Spaanderman, Guido de Jong   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source