Results 61 to 70 of about 3,436,268 (369)

Human neural stem cell transplantation in ALS: initial results from a phase I trial [PDF]

, 2015
We report the initial results from a phase I clinical trial for ALS. We transplanted GMP-grade, fetal human neural stem cells from natural in utero death (hNSCs) into the anterior horns of the spinal cord to test for the safety of both cells and ...
Bernardini, Laura, Bersano, Enrica, Binda, Elena, Boulis, Nicholas M, Cantello, Roberto, Carletti, Sandro, Carriero, Alessandro, Cerino, Annalisa, Cima, Valentina, Cisari, Carlo, Domenico, Frondizi, Ferrari, Daniela, Gaiani, Alessandra, Gelati, Maurizio, Giorgi, Cesare, Glass, Jonathan, Maglione, Annamaria, Masiero, Stefano, Massara, Maurilio, Mazzini, Letizia, Muzi, Gianmarco, Nasuelli, Nicola, Novelli, Antonio, Petruzzelli, Francesco, Prandi, Paolo, Profico, Daniela Celeste, Projetti Pensi, Massimo, Querin, Giorgia, Ricciolini, Claudia, Rota Nodari, Laura, Sarnelli, Maria Francesca, Servo, Serena, Sgaravizzi, Giada, Soraru', Gianni, Spera, Cristina, Stecco, Alessandro, Torres, Barbara, Trombetta, Domenico, Vescovi, Angelo L., Visioli, Alberto, Zalfa, Cristina   +40 more
core   +2 more sources

Pseudomeningocele after in utero repair of myelomeningocele as an early sign of hypertensive hydrocephalus – a case report and review of the literature

Archives of Pediatric Neurosurgery, 2021
Background Myelomenigocele (MMC) is the most common congenital defect of the spine. The Management of Myelomeningocele study (MOMS trial) demonstrated that the prenatal repair decreased shunt implant, reversal of hindbrain herniation and better ...
Daniel Dante Cardeal, Ingrid Schwach Werneck Britto, Sandra Rejane Silva Herbst, Milton Hikaru Toita, Gabriela Duarte Bordini, José Carlos Esteves Veiga, Rodrigo Ruano   +6 more
doaj   +1 more source

Non-obstetric surgery during pregnancy and the effects on maternal and fetal outcomes: A systematic review

Scandinavian Journal of Surgery, 2023
Background and objective: Non-obstetric surgery is fairly common in pregnant women. We performed a systematic review to update data on non-obstetric surgery in pregnant women.
Anna Haataja, H. Kokki, O. Uimari, M. Kokki   +3 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Quantifying prenatal and postnatal mortality in extreme early onset fetal growth restriction: A systematic review and incidence analysis

Pregnancy
Background and Objective Extreme early‐onset fetal growth restriction (EE‐FGR) is associated with significant perinatal morbidity and mortality. As short‐ and long‐term prognoses are influenced by both gestational age and severity of FGR, quantifying ...
Shohra Qaderi, Giulia Bonanni, Mohammadamin Parsaei, Ehsan Rojhani, Satjeet Deol Chauhan, Eyal Krispin, Dario O. Fauza, Anna L. David, Kjersti Aagaard, Alireza A. Shamshirsaz   +9 more
doaj   +1 more source

Placental Vessel Segmentation Using Pix2pix Compared to U-Net

Journal of Imaging, 2023
Computer-assisted technologies have made significant progress in fetoscopic laser surgery, including placental vessel segmentation. However, the intra- and inter-procedure variabilities in the state-of-the-art segmentation methods remain a significant ...
Anouk van der Schot, Esther Sikkel, Marèll Niekolaas, Marc Spaanderman, Guido de Jong   +4 more
doaj   +1 more source

Conference scene : Golden Helix Pharmacogenomics Days : educational activities on pharmacogenomics and personalized medicine [PDF]

, 2012
The Golden Helix Pharmacogenomics Days are high-profile international educational scientific meetings discussing pharmacogenomics and personalized medicine.
Borg, Joseph J., Fenech, Anthony G., Grech, Godfrey, Patrinos, George P., Severino, Giovanni, Squassina, Alessio   +5 more
core   +2 more sources

Challenging the 'Born Alive' Threshold: Fetal Surgery, Artificial Wombs, and the English Approach to Legal Personhood.

Medical Law Review, 2019
English law is unambiguous that legal personality, and with it all legal rights and protections, is assigned at birth. This rule is regarded as a bright line that is easily and consistently applied.
E. C. Romanis
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source