Results 271 to 280 of about 378,578 (295)
, 1993 During the past decade, major advances have been made in the techniques used for prenatal diagnosis and in our understanding of anatomic, physiologic, and molecular pathologies that adversely affect fetal development. At the same time, there has also been considerable attention directed toward the development of strategies for fetal therapy.
Sherman Elias, Owen P. Phillips
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Der Gynäkologe, 1999
Although most prenatally diagnosed anatomic malformations are best managed after birth, we can presently offer prenatal therapy to an increasing number of fetuses with simple anatomical defects that have predictably devastating developmental consequences. A condition amenable to prenatal intervention must fulfill a number of conditions.
B. Paek +4 more
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Although most prenatally diagnosed anatomic malformations are best managed after birth, we can presently offer prenatal therapy to an increasing number of fetuses with simple anatomical defects that have predictably devastating developmental consequences. A condition amenable to prenatal intervention must fulfill a number of conditions.
B. Paek +4 more
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Ethical issues in fetal therapy
Best Practice & Research Clinical Obstetrics & Gynaecology, 2017The introduction of routine fetal ultrasound and the technical improvements in ultrasound equipment have greatly increased our ability to diagnose fetal anomalies. As a consequence, congenital anomalies are diagnosed today earlier and in a greater number of patients than ever before.
Amirhossein Moaddab +3 more
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Fetal Cardiovascular Physiology and Therapy
Fetal Diagnosis and Therapy, 1992The ability to diagnose fetal cardiovascular malformations prenatally has been established during the past 14 years. This has naturally led to an increased interest in the possibility of providing timely therapy in the neonatal period and has raised the prospects for prenatal intervention.
Charles S. Kleinman, Joshua A. Copel
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The Ultrasound Review of Obstetrics and Gynecology, 2001
ABSTRACTFetal gene therapy has the potential to treat inherited genetic diseases in utero before significant organ damage has occurred. Rapidly expanding stem cell populations may be targeted and the introduction of transgenes to the fetus during development of the immune system could result in immune tolerance and facilitate repeat treatment ...
Charles Coutelle +4 more
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ABSTRACTFetal gene therapy has the potential to treat inherited genetic diseases in utero before significant organ damage has occurred. Rapidly expanding stem cell populations may be targeted and the introduction of transgenes to the fetus during development of the immune system could result in immune tolerance and facilitate repeat treatment ...
Charles Coutelle +4 more
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The Obstetrician & Gynaecologist, 2010
Key content Fetal medicine is a rapidly developing subspecialty. The mainstay of treatment for fetal alloimmune thrombocytopenia remains maternal immunoglobulin therapy. Stem cell transplantation and gene therapy have advanced over the last decade but must still be considered experimental. Laser coagulation is the best treatment for all stages of twin‐
Ben C Chan +2 more
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Key content Fetal medicine is a rapidly developing subspecialty. The mainstay of treatment for fetal alloimmune thrombocytopenia remains maternal immunoglobulin therapy. Stem cell transplantation and gene therapy have advanced over the last decade but must still be considered experimental. Laser coagulation is the best treatment for all stages of twin‐
Ben C Chan +2 more
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1993
Historically, the fetus has been an object of mystery and obscurity. From conception to delivery, its development has been hidden, isolated in the mother with only the presumption of well-being until the time of birth. The distress attendant at the birth of an abnormal fetus has spurred efforts to demystify this development.
Mitchell S. Golbus, Melissa M. Fries
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Historically, the fetus has been an object of mystery and obscurity. From conception to delivery, its development has been hidden, isolated in the mother with only the presumption of well-being until the time of birth. The distress attendant at the birth of an abnormal fetus has spurred efforts to demystify this development.
Mitchell S. Golbus, Melissa M. Fries
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Obstetrics, Gynaecology & Reproductive Medicine, 2015
Abstract The specialty of fetal medicine has benefited from advances in technology in recent years, improving maternal and fetal outcomes. This review considers four case studies to illustrate some of the challenging and complex pregnancies that present to this field of medicine.
Timothy G. Overton +3 more
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Abstract The specialty of fetal medicine has benefited from advances in technology in recent years, improving maternal and fetal outcomes. This review considers four case studies to illustrate some of the challenging and complex pregnancies that present to this field of medicine.
Timothy G. Overton +3 more
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Minimally invasive fetal therapy
Best Practice & Research Clinical Obstetrics & Gynaecology, 2012The implementation of systematic pregnancy screening programmes, and the increased use and improving quality of medical imaging techniques, have lead to earlier detection and better understanding of the natural history of fetal anomalies. Where most fetal conditions are adequately treatable after birth, some disorders progress during fetal life and can
Liesbeth Lewi +7 more
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Current Obstetrics & Gynaecology, 1995
It is now possible to successfully treat several fetal disorders in utero. Early enthusiasm for fetal surgery has declined, and now such intervention is rarely considered. In contrast, there are an increasing number of circumstances in which fetal drug therapy appears to have a role either in treating a fetal disorder or improving the capacity of the ...
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It is now possible to successfully treat several fetal disorders in utero. Early enthusiasm for fetal surgery has declined, and now such intervention is rarely considered. In contrast, there are an increasing number of circumstances in which fetal drug therapy appears to have a role either in treating a fetal disorder or improving the capacity of the ...
openaire +2 more sources