Results 101 to 110 of about 4,656,954 (331)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

ASSESSMENT OF TOMATO STAMPING VARIETIES IN IRRIGATED CONDITIONS IN THE LOWER VOLGA REGION

Овощи России, 2018
The article discusses the results of two years experiments to study the morphological and biological parameters stam varieties of tomato. Stam samples were taken in the breeding gene pool of tomato, characterized by the length of the stem.
V. I. Donskaya, N. H. Katakaev
doaj   +1 more source

Additive drug-specific and sex-specific risks associated with co-use of marijuana and tobacco during pregnancy: Evidence from 3 recent developmental cohorts (2003-2015). [PDF]

, 2018
BACKGROUND: Methodologic challenges related to the concomitant use (co-use) of substances and changes in policy and potency of marijuana contribute to ongoing uncertainty about risks to fetal neurodevelopment associated with prenatal marijuana use.
Eiden, Rina D, Ganiban, Jody M, Graham, Eileen K, Huestis, Marilyn A., Jakubowski, Jessica A, Leve, Leslie D, Massey, Suena H, McCallum, Meaghan, Miller, Emily S, Mroczek, Daniel K, Neiderhiser, Jenae M, Reiss, David, Shaw, Daniel S, Shisler, Shannon M, Stroud, Laura R   +14 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

FETAL DISCORDANCY IN MONOCHORIONIC TWINS

Акушерство, гинекология и репродукция, 2016
Objective: to investigate the predictive value of fetal weight discordance as a risk factor associated with adverse perinatal outcomes. Materials and Methods: 55 patients with monochorionic diamniotic twin pregnancies with fetal weight discordancy were ...
L. G. Sichinava, O. B. Panina, K. G. Gamsakhurdiya   +2 more
doaj   +1 more source

Placental DEPTOR as a stress sensor during pregnancy [PDF]

, 2011
The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and ...
Gidron, Y, Goumenou, A, Karteris, E, Mparmpakas, D, Zachariades, E   +4 more
core   +2 more sources

Determination of Accuracy of Fetal Weight Using Ultrasound and Clinical Fetal Weight Estimations in Calabar South, South Nigeria

International Scholarly Research Notices, 2014
Information on fetal weight is of importance to obstetricians in the management of pregnancy and delivery. The objective of this study is to compare the accuracy of clinical and sonographic methods of predicting fetal weights at term.
C. Njoku, C. Emechebe, P. Odusolu, Sylvestre Abeshi, C. Chukwu, J. Ekabua   +5 more
semanticscholar   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Estimation of Fetal Birth Weight Using Ultra Sonographic Parameters

Journal of Nepal Medical Association, 2013
One hundred antenatal patients were studied at term pregnancy at Gauhati Medical College, Guwahati, and fetal birth weight estimation was done in utero Ultrasono-graphically. The parameters measured were Abdominal Circumference (AC), Biparietal diameter (
Kaveeta Dawaka, G C Das
doaj   +1 more source

Associations between Knowledge in Antenatal Nutrition, Family Income, Placenta Width, and Fetal Weight, at Mother and Child Hospital Arvita Bunda, Sleman, Yogyakarta [PDF]

, 2017
Background: Fetal growth and development are influnced by many factors, including maternal knowledge in nutrition intake. The nutrients obtained from maternal food intake are transferred to the fetus through placenta, thereby affecting placental width ...
Murti, B. (Bhisma), Nurtyas, M. (Maratusholikhah), Wudjoso, H. (Hari)   +2 more
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