Results 41 to 50 of about 419,067 (303)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Anatomohistological characteristics of Meckel's diverticulum in human fetuses [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. Meckel's diverticulum (MD) is the most frequent anomaly of the small intestine. It appears after incomplete obliteration of the omphalomesenteric or viteline duct which normally obliterates and disappears by the 9th week of gestation. The
Pavlović Snežana   +5 more
doaj   +1 more source

Even if the fetus is not a person, abortion is immoral: The impairment argument [PDF]

open access: yes, 2019
Much of the discussion surrounding the ethics of abortion has centered around the notion of personhood. This is because many philosophers hold that the morality of abortion is contingent on whether the fetus is a person - though, of course, some famous ...
Hendricks, Perry
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Quality Characteristics of Concrete Poles Manufactured in the Ibadan Metropolis, Southwest Nigeria [PDF]

open access: yes, 2012
In Nigeria, power is transmitted by overhead transmission lines fixed on wooden or concrete poles. Often times these poles collapse under excessive loads occasioned by storm and accidents.
Fashola, A.A., Oyawale, Fetus A
core  

Fetus in Fetu [PDF]

open access: yesJournal of Diagnostic Medical Sonography, 2009
Fetus in fetu is a congenital abnormality in which a nonviable, parasitic fetus grows within its twin. It is a rare cause of retroperitoneal abdominal mass in infants and children. The authors report a recent case of a six-month-old girl who presented with unexplained abdominal distention. A sonogram and a magnetic resonance imaging examination showed
Hamad Ghazle, Kimberly Dolbow
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Brain food for babies [PDF]

open access: yes, 2017
How does a mother supply a key building block of the brain required for neurodevelopment to her fetus in pregnancy? The critical requirement of docosahexaenoic acid (DHA) for fetal brain development, and the poor efficiency of its synthesis in humans, is
Freeman, Dilys J., Meyer, Barbara J.
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Christianity Views Fetal Research [PDF]

open access: yes, 1978
The development of defense forces is always confronted with the problem of resource constraints, including national funding sources that are faced with other priority national policy options.
Quinn, James J.
core   +7 more sources

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