LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Re: Impact on obstetric outcome of third‐trimester screening for small‐for‐gestational‐age fetuses. R. Callec, C. Lamy, E. Perdriolle‐Galet, C. Patte, B. Heude and O. Morel. Ultrasound Obstet Gynecol 2015; 46: 216–220 [PDF]
, 2015 Žarko Alfirević
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Placental Infection with Different SARS-CoV-2 Variants Leading to Stillbirth: Report of Two Cases
COVIDSARS-CoV-2 placental infection, also known as placentitis (SP), is an established cause of stillbirth; however, this pathology is rare and its incidence across different viral variants is unknown.
Miriam A. Snow +4 more
doaj +1 more source
OP01.03: Development of an endocavity ultrasound and photoacoustic imaging device for non‐invasive assessment of blood oxygenation and perfusion in fetuses and neonates [PDF]
, 2019 Mohammad Mehrmohammadi +2 more
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Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb) [PDF]
, 2022 Shintaro Maki +29 more
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Frontiers in Cardiovascular MedicineObjectiveThe aim was to summarise the prenatal ultrasound characteristics, associated anomalies and pregnancy outcomes of fetal right aortic arch (RAA) and to discuss the value of prenatal ultrasound diagnosis and prognostic analysis.MethodsWe ...
Yuting Xie +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source