Results 81 to 90 of about 423,269 (300)

Maternal-fetal attachment among Vietnamese mothers in the first, second, and third trimesters of pregnancy: A pilot study. [PDF]

, 2004
Purpose: The purpose of this study was to investigate maternal-fetal attachment (MFA) among Vietnamese women during pregnancy. Design: This study is a quantitative, descriptive pilot study of maternal fetal attachment among twenty-five Vietnamese women ...
Choo, Barbara
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Detection of markers of rubella in risk groups of children

Журнал инфектологии, 2014
The examination of newborn infants with perinatal pathology and dead children threatened by congenital rubella syndrome was conduct. It was established that the dead fetuses and newborns markers of rubella virus were more common than living children, and
N. L. Rogushina, O. V. Samodova, L. V. Titova, L. V. Voinova   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Polystyrene nanoplastics modulate the transformation of silver ions in the dark: Key role of environmentally persistent free radicals

Water Research X
The co-occurrence of nanoplastics (NPs) and Ag+ has drawn public attention, and NPs-driven transformation of Ag⁺ has been widely documented under sunlight. However, the role of NPs in Ag+ transformation remains poorly understood under dark conditions. We
Peng Duan, Dandan Shi, Zhoujie Jang, Yujie Jin, Chunhui Hu, Weicheng Zhang   +5 more
doaj   +1 more source

Cytomegalovirus infection and congenital heart disease in children

Журнал инфектологии, 2019
Congenital heart defects account for about 30% of all anomaly of development in children. Cytomegalovirus infection suffered by a woman during pregnancy claims one of the leading places among teratogenic factors.Aim: to study clinical and pathogenetic ...
E. A. Каshuba, Yu. S. Chehova, K. V. Gorbatikov, T. G. Drozdova, I. S. Totolin, М. V. Аntonova, Е. Yu. Savinova   +6 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Exploring factors affecting malaria vaccination intention and COVID-19 vaccine uptake: evidence from a joint analysis in rural Senegal

BMC Public Health
Background Current malaria vaccination efforts target infants from 5 months of age; however, adult malaria mortality remains a significant and under-reported issue in high-transmission settings.
S. Cortaredona, C. Sokhna, G. Maradan, EH. Ba, V. Seror, the CO3ELSER group   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source