Results 211 to 220 of about 1,544,983 (360)

Phase 2 results of lisocabtagene maraleucel in Japanese patients with relapsed/refractory aggressive B‐cell non‐Hodgkin lymphoma

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4889-4899, December 2022., 2022
This analysis assessed safety and efficacy of lisocabtagene maraleucel (liso‐cel), an autologous CD‐19‐directed CAR T‐cell product, in Japanese patients with R/R aggressive LBCL in Cohort 3 of TRANSCEND WORLD (NCT03484702). Liso‐cel demonstrated meaningful efficacy and a manageable safety profile in Japanese patients with R/R LBCL.
Shinichi Makita   +11 more
wiley   +1 more source

Fevogrit, a polyherbal medicine, mitigates endotoxin (lipopolysaccharide)‐induced fever in Wistar rats by regulating pro‐inflammatory cytokine levels

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Fevogrit, an Ayurvedic medicine indicated for the management of fever, was evaluated for its pharmacological effects in rat model of endotoxin (lipopolysaccharide)‐induced high body temperature. Ultra‐high‐performance liquid chromatography analysis revealed the presence of bioactive phytometabolites in Fevogrit.
Acharya Balkrishna   +7 more
wiley   +1 more source

Health‐related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population‐based cohort study

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro   +4 more
wiley   +1 more source

Application of humanized mice in the safety experiments of antibody drugs

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun   +9 more
wiley   +1 more source

Animal models of human herpesvirus infection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Human herpesvirus can infect humans and other vertebrates, primarily targeting the skin, mucous membranes, and neural tissues, thereby significantly impacting the health of both humans and animals. Animal models are crucial for studying virus pathogenesis, vaccine development, and drug testing.
Ziqing Jia   +3 more
wiley   +1 more source

Diagnosing and Preventing Q Fever in Regional New South Wales, Australia-A Qualitative Exploration of Perspectives of General Practitioners. [PDF]

open access: yesAust J Rural Health
Maduranga S   +10 more
europepmc   +1 more source

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