Results 51 to 60 of about 1,463,292 (235)
Memórias do Instituto Oswaldo Cruz, 2000 With the infestation by Aedes aegypti, urban yellow fever might already exist. This did not occur because of either the lacking of a sufficient contact between the diseased individual and the A. aegypti or perhaps because this, after sixty years without transmitting the virus, needs an adaptation phase to infecting again.
openaire +5 more sources
An Outbreak of Q fever in a prison in Italy [PDF]
, 2005 We observed an outbreak of Q fever in a prison population. Overall, 65 of the 600 prison inmates developed the disease. The location of the prison cells had no apparent effect on the risk of infection.
Babudieri, Sergio +5 more
core +1 more source
Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System
Advanced Science, EarlyView.This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao +7 more
wiley +1 more source
Spatial analysis of risk factors for childhood morbidity in Nigeria [PDF]
, 2007 Recent Demographic and Health Surveys (DHS) from Sub-Saharan Africa (SSA) indicate a decline in childhood vaccination coverage but a high prevalence of childhood diarrhea, cough, and fever.
Cappuccio, Francesco +4 more
core
Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
Advanced Science, EarlyView.The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su +12 more
wiley +1 more source
Familial Mediterranean Fever without Fever
Internal Medicine, 2020 Familial Mediterranean fever (FMF) is an autosomal recessive hereditary disease commonly observed around the Mediterranean basin presenting as recurrent febrile episodes. We herein describe a Japanese case of genetically-confirmed FMF, in which fever was lacking during attacks.
Hirokazu Oyamada +11 more
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Hematology/Oncology Clinics of North America, 2014 Fever is a common presenting complaint among adult or pediatric patients in the emergency department setting. Although fever in healthy individuals does not necessarily indicate severe illness, fever in patients with neutropenia may herald a life-threatening infection.
Lindsey, White, Michael, Ybarra
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The return of brucellosis [PDF]
, 1995 Brucellosis, also known under the names of Undulant fever, Mediterranean fever and Malta fever is closely linked with Malta’s medical history and for long endemic to our Islands.
Amato-Gauci, Andrew J.
core
Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion [PDF]
, 2010 Expert opinion was elicited to undertake a qualitative risk assessment to estimate the current and future risks to the European Union (EU) from five vector-borne viruses listed by the World Organization for Animal Health.
Brouwer, A. +7 more
core +1 more source
Advanced Science, EarlyView.Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li +13 more
wiley +1 more source