Results 51 to 60 of about 169 (160)

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Carboxylate‐Driven Metal Pre‑Fixation COF@MOF Synthesis: Enabling Tailored Structural, Dimensional, and Defect Engineering

Advanced Science, EarlyView.
A universal metal pre‐fixation (MPF) strategy directs the precise crystallization of diverse metal‐organic frameworks (Co‐MOF, ZIF‐8, Fe‐MOF, UIO‐66) on covalent organic framework (PY‐COF) scaffolds. The resulting hierarchical hybrids exhibit tunable porosity, structural defective and dimensional, as well as enhanced performance in CH4/C2H6/C3H8 ...
Ying Zhao, Dongmei Chen, Huilin Zheng, Min Chen, Dingtang Li, Shuyu Xie   +5 more
wiley   +1 more source

Factors Affecting Recollapse of the Augmented Vertebrae After Percutaneous Vertebral Augmentation: A Prospective Study

AGING MEDICINE, EarlyView.
To investigate the relevant factors of augmented vertebrae recollapse after percutaneous vertebral augmentation (PVA) for the treatment of osteoporotic vertebral compression fractures (OVCFs). Intervertebral cleft (IVC) and those with PVP intervention are at higher risk of recollapse.
Yawen Zhang, Junchuan Liu, Maoyu Zhao, Yudian Qiu, Quan Ji, Nan Min, Qiang Wang   +6 more
wiley   +1 more source

Preoperative Gemcitabine/Nab‐Paclitaxel With Concurrent Radiation Therapy for Borderline Resectable Pancreatic Cancer: A Comparative Analysis With Preoperative Chemoradiation Therapy Using Gemcitabine Alone

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although NCCN guidelines recommend preoperative therapy for borderline resectable pancreatic cancer (BR‐PC), it is still unclear which regimen is better. The study objective was to elucidate the prognostic significance of neoadjuvant chemoradiotherapy (NACRT) with gemcitabine/nab‐paclitaxel (GnP‐RT) compared to gemcitabine alone ...
Hirofumi Akita, Hidenori Takahashi, Yousuke Mukai, Masahiko Kubo, Shinichiro Hasegawa, Masayoshi Yasui, Takeshi Omori, Hiroshi Miyata, Hiroshi Wada, Kunihito Gotoh   +9 more
wiley   +1 more source

Association of a Multimodal Perioperative Care Program With Postoperative Complications in Elderly Patients Undergoing Gastrectomy for Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
Implementation of a multimodal perioperative care program and reduction of postoperative complications. ABSTRACT Purpose This retrospective study aimed to assess the clinical effectiveness of a multimodal perioperative care program in reducing postoperative complications in elderly patients undergoing gastrectomy for gastric cancer.
Keiichi Fujiya, Hiroshi Fuseya, Yusuke Yonenaga, Keiko Sanada, Toshimi Inano, Yumi Oguma, Kazuko Nakajima, Chikako Ando, Kumiko Oka, Yusuke Koseki, Kenichiro Furukawa, Yutaka Tanizawa, Masanori Terashima, Etsuro Bando   +13 more
wiley   +1 more source

Potential Survival Benefit of Neoadjuvant Docetaxel, Cisplatin and 5‐Fluorouracil Therapy in Patients With Esophageal Squamous Cell Carcinoma With Multiple Lymph Node Metastases: A Single‐Institute Propensity Score Analysis

Annals of Gastroenterological Surgery, EarlyView.
Although neoadjuvant chemotherapy with fluorouracil, cisplatin, and docetaxel (NAC‐DCF) is the current standard neoadjuvant regimen for esophageal squamous cell carcinoma, its substantial toxicity underscores the need to identify patients who derive the greatest benefit.
Eiji Higaki, Tetsuya Abe, Hironori Fujieda, Shigenori Kadowaki, Tsutomu Tanaka, Masahiro Tajika, Koji Komori, Seiji Ito, Isao Oze, Kei Muro   +9 more
wiley   +1 more source

Can Machine Learning Reduce Unnecessary Surgeries? A Retrospective Analysis Using Threshold Optimization to Prevent Negative Appendectomies in Adults

Annals of Gastroenterological Surgery, EarlyView.
Threshold‐optimized machine learning models using routine clinical and laboratory data in 623 adults undergoing appendectomy. Logistic regression (AUC = 0.765) and random forest (AUC = 0.785) were the best‐performing models for appendicitis detection and complicated appendicitis prediction, respectively.
Ivan Males, Marko Kumric, Zvonimir Boban, Josip Vrdoljak, Dario Pecenkovic, Matej Ivanda, Marko Grahovac, Zenon Pogorelic, Josko Bozic   +8 more
wiley   +1 more source

Smart Denture with Embedded Thin‐Film Temperature Sensors Patterned by Femtosecond Laser Pulse for Elderly Healthcare

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam, Yong Kwon Chae, Seoung‐Jin Hong, Younggen Lee, Dongwook Yang, Byunggi Kim, Sang Wook Kang, Young‐Jin Kim   +7 more
wiley   +1 more source

The Herfindahl neutral point: A firm‐level threshold for managing market concentration with evidence from US hog packing

American Journal of Agricultural Economics, EarlyView.
Abstract This paper derives a firm‐level threshold, the Herfindahl Neutral Point, from the standard concentration index used in merger review. At this threshold, a marginal expansion leaves the index unchanged. Firms below the threshold reduce concentration when they expand; firms above it increase concentration.
Andrew J. Keller, Krishna P. Paudel
wiley   +1 more source

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

American Journal of Hematology, EarlyView.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao, Nicolas Stocker, Béatrice Gaugler, Mohamad Mohty, Florent Malard   +4 more
wiley   +1 more source