Results 121 to 130 of about 54,797 (285)

Placental malaria induces a unique methylation profile associated with fetal growth restriction

Epigenetics
Fetal growth restriction (FGR) is associated with perinatal death and adverse birth outcomes, as well as long-term complications, including increased childhood morbidity, abnormal neurodevelopment, and cardio-metabolic diseases in adulthood.
Nida Ozarslan, Corina Mong, John Ategeka, Lin Li, Sirirak Buarpung, Joshua F. Robinson, Jimmy Kizza, Abel Kakuru, Moses R. Kamya, Grant Dorsey, Philip J. Rosenthal, Stephanie L. Gaw   +11 more
doaj   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck.

Journal of Immunology, 1999
Polymorphonuclear neutrophils (PMN) adherent to integrin ligands respond to inflammatory mediators by reorganizing their cytoskeleton and releasing reactive oxygen intermediates.
A. Mócsai, A. Mócsai, E. Ligeti, C. Lowell, Giorgio Berton   +4 more
semanticscholar   +1 more source

Fetal Left Ventricle Function Evaluated by Two-Dimensional Speckle-Tracking Echocardiography across Clinical Stages of Severity in Growth-Restricted Fetuses

Diagnostics
Fetal growth restriction (FGR) can result in adverse perinatal outcomes due to cardiac dysfunction. This study used 2D speckle-tracking echocardiography to assess left ventricle (LV) longitudinal strain across FGR severity stages.
Carla Domínguez-Gallardo, Nuria Ginjaume-García, Johana Ullmo, Juan Parra, Ana Vázquez, Mónica Cruz-Lemini, Elisa Llurba   +6 more
doaj   +1 more source

Non-Markovian decay beyond the Fermi Golden Rule: Survival Collapse of the polarization in spin chains

, 2009
The decay of a local spin excitation in an inhomogeneous spin chain is evaluated exactly: I) It starts quadratically up to a spreading time t_{S}. II) It follows an exponential behavior governed by a self-consistent Fermi Golden Rule.
Anderson, Baum, Chiu, Cucchietti, Danieli, Danieli, DiVicenzo, Doronin, D’Amato, E. Rufeil Fiori, Elattari, Facchi, Fano, Fonda, Gamow, García-Calderón, García-Calderón, Gurney, H.M. Pastawski, Hu, Keldysh, Khalfin, Kofman, Krylov, Levstein, Lieb, Mádi, Pastawski, Pastawski, Pastawski, Pastawski, Pastawski, Stolze, Thouless, Usaj, Wilkinson, Wisniacki   +36 more
core   +1 more source

Moderate Diagnostic Yield of Exome Sequencing in Fetal Growth Restriction: Retrospective Insights

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To determine whether invasive genetic testing should be systematically proposed in cases of FGR. Methods Descriptive retrospective study of 159 FGR cases (defined by an estimated fetal growth < 3rd percentile, regardless of Doppler findings) managed at the Toulouse Fetal Medicine Center (TFMC) during 2022–2023.
Maud Langeois, Louise Paret, Jacqueline Aziza, Paul Guerby, Christophe Vayssière, Charlotte Dubucs   +5 more
wiley   +1 more source

PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcRγ to induce slow leukocyte rolling

Journal of Experimental Medicine, 2008
E-selectin binding to P-selectin glycoprotein ligand-1 (PSGL-1) can activate the β2 integrin lymphocyte function-associated antigen-1 by signaling through spleen tyrosine kinase (Syk).
A. Zarbock, C. Abram, M. Hundt, A. Altman, C. Lowell, K. Ley   +5 more
semanticscholar   +1 more source

The Loschmidt Echo as a robust decoherence quantifier for many-body systems

, 2012
We employ the Loschmidt Echo, i.e. the signal recovered after the reversal of an evolution, to identify and quantify the processes contributing to decoherence.
A. Abragam, Axel D. Dente, C. P. Slichter, Horacio M. Pastawski, M. Rieth, M. S. Grinolds, Pablo R. Zangara, Patricia R. Levstein, U. Weiss, W. H. Zurek   +9 more
core   +1 more source

Fetal cardiac remodeling in second trimester in pregnancies with pre‐eclampsia and/or fetal growth restriction: deep‐learning‐based approach using population‐wide data

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Pre‐eclampsia (PE) and fetal growth restriction (FGR) have been shown to impact fetal cardiac remodeling in the third trimester and postnatally, with evidence to suggest that this leads to increased long‐term cardiovascular risk. This study aimed to examine fetal cardiac remodeling in pregnancies with PE and/or FGR during the second ...
C. A. Taksøe‐Vester, K. Mikolaj, O. B. Petersen, C. K. Ekelund, N. G. Vejlstrup, C. Vedel, A. N. Christensen, A. Feragen, M. Nielsen, M. G. Tolsgaard   +9 more
wiley   +1 more source

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity.

Genes & Development, 1994
We have generated mice with targeted disruptions of the src-like genes hck and fgr to assess the role of these kinases in myeloid cell development and function.
C. Lowell, Philippe Soriano, H. Varmus
semanticscholar   +1 more source