Results 151 to 160 of about 54,797 (285)

Bruton tyrosine kinase (Btk) in neutrophils is indispensable for initiating and maintaining skin inflammation in a model of pemphigoid diseases

British Journal of Pharmacology, EarlyView.
Background and Purpose Bruton tyrosine kinase (Btk) is essential for B cell function. Its role in myeloid cells is less understood. Greater insights into Btk significance in myeloid cells are needed to evaluate its potential as a therapeutic target during the effector phase of antibody‐induced autoimmune diseases, where inhibiting autoantibody ...
Henning Olbrich, Paul Schilf, Sripriya Murthy, Sina Gonther, Mareike Neumann, Christoph M. Hammers, Jasper N. Pruessmann, Christian D. Sadik   +7 more
wiley   +1 more source

Disproportional ventilatory response to incremental exercise in individuals with cerebral palsy

Developmental Medicine &Child Neurology, EarlyView.
Individuals with cerebral palsy demonstrate a disproportionate ventilatory response during incremental exercise. Compared with typically developing peers, respiratory frequency increases earlier and at comparable exercise intensities, contributing to higher perceived exertion and reduced ventilatory efficiency. At task failure, respiratory frequency is
Linnéa Corell, Emma Hjalmarsson, Rodrigo Fernandez‐Gonzalo, Annika Kruse, Sebastian Edman, Asta Kizyte, Rouli Wang, Arnoud Edelman Bos, Peder Sörensson, Eva Pontén, Petra E. M. van Schie, Annemieke I. Buizer, Jessica Norrbom, Daniele A. Cardinale, Ferdinand von Walden   +14 more
wiley   +1 more source

The search for the ultimate exercise countermeasure to preserve crew health and ensure mission success in long‐duration spaceflight

Experimental Physiology, EarlyView.
Abstract The current understanding of crew health maintenance is founded upon decades of physiological research conducted in terrestrial spaceflight analogues and in low Earth orbit, particularly on the International Space Station. However, as we progress towards the Lunar Gateway and interplanetary missions, it is imperative that the tools employed to
Rodrigo Fernandez‐Gonzalo, Stefan Schneider, Martina Heer, Anna‐Maria Liphardt   +3 more
wiley   +1 more source

Antenatal betamethasone impairs markers of cardiac development and function in near‐term lambs

Experimental Physiology, EarlyView.
Abstract figure Summary of key molecular differences in the left ventricle of near‐term lambs exposed to antenatal betamethasone, compared to saline. Pregnant ewes received two doses of either saline (Saline) or betamethasone (Betamethasone, intramuscular, 11.4 mg) given 24 h apart, before delivery at 140 days of gestation (dG, term = 150 dG).
Reza Amanollahi, Ashley S. Meakin, Stacey L. Holman, Vicki L. Clifton, Kent L. Thornburg, Michael D. Wiese, Kathryn L. Gatford, Mitchell C. Lock, Janna L. Morrison   +8 more
wiley   +1 more source

Limited musculoskeletal benefits of artificial gravity combined with cycling during bed rest: Results from the BRACE study

Experimental Physiology, EarlyView.
Abstract Prolonged exposure to microgravity, simulated via 6° head‐down tilt bed rest (HDT), induces musculoskeletal deconditioning and negatively impacts body composition. This study evaluated whether a combination of aerobic exercise with artificial gravity (AG) offers superior protection in comparison to exercise alone.
Mirko Mandić, Tommy R. Lundberg, Jean‐Pol Frippiat, Adam C. McDonnell, Igor B. Mekjavić, Marie‐Pierre Bareille, Rebecca Billette de Villemeur, Rodrigo Fernandez‐Gonzalo   +7 more
wiley   +1 more source

Antenatal identification of early- and late-onset fetal growth restriction and the possible impact of the introduction of cerebroplacental ratio: Effect on perinatal and childhood outcome.

PLoS ONE
ObjectiveTo investigate the effect of antenatal identification of small for gestational age (SGA) fetuses on perinatal and childhood outcomes, separately analyzing early- and late-onset fetal growth restriction (FGR).Materials and methodsA register-based
Emma Hertting, Lotta Herling, Pelle G Lindqvist, Eva Wiberg-Itzel   +3 more
doaj   +1 more source

Maternal factors and perinatal outcomes associated with early-onset versus late-onset fetal growth restriction: a meta-analysis

The Journal of Maternal-Fetal & Neonatal Medicine
Background Fetal growth restriction (FGR) is considered to be one of the most common causes of adverse perinatal outcomes. This study conducted a meta-analysis of the maternal factors and perinatal outcomes associated with early-onset FGR (EO-FGR ...
Cecilia Putri Tedyanto, Fransiscus Octavius Hari Prasetyadi, Sianty Dewi, Harnoprihadi Noorlaksmiatmo   +3 more
doaj   +1 more source

Timing of Delivery in Preeclampsia: Time to Reconsider?

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Rebecca Horgan, Ahmed S. Z. Moustafa, Mackenzi Mchugh, Tetsuya Kawakita, Baha Sibai, George Saade   +5 more
wiley   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

The Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford, Georgia Fakonti, Ziyu Shao, Sharanam Soni, Sophie L. Earle, Muath Bajarwan, Lara C. Morley, Beth Holder, Eleanor M. Scott, Karen Forbes   +9 more
wiley   +1 more source

FGR Fitness

, 2016
En este informe se presenta un sistema web de gestión de un club deportivo, denominado FGR Fitness. El cometido de esta plataforma es ofrecer en un único entorno web los servicios que toda organización deportiva busca en un sistema de estas características. Así pues, permite la gestión de usuarios, actividades y comunicación.
openaire   +1 more source