Results 11 to 20 of about 54,797 (285)

Ionizing irradiation-induced Fgr in senescent cells mediates fibrosis [PDF]

Cell Death Discovery, 2021
AbstractThe role of cellular senescence in radiation-induced pulmonary fibrosis (RIPF) and the underlying mechanisms are unknown. We isolated radiation-induced senescent tdTOMp16 positive mesenchymal stem cells, established their absence of cell division, then measured levels of irradiation-induced expression of biomarkers of senescence by RNA-seq ...
Amitava Mukherjee, Michael W. Epperly, Donna Shields, Wen Hou, Renee Fisher, Diala Hamade, Hong Wang, M. Saiful Huq, Riyue Bao, Tracy Tabib, Daisy Monier, Simon Watkins, Michael Calderon, Joel S. Greenberger   +13 more
openaire   +4 more sources

Sex-Biased lncRNA Signature in Fetal Growth Restriction (FGR) [PDF]

Cells, 2021
Impaired fetal growth is one of the most important causes of prematurity, stillbirth and infant mortality. The pathogenesis of idiopathic fetal growth restriction (FGR) is poorly understood but is thought to be multifactorial and comprise a range of genetic causes.
Aleksandra Lipka, Jan Pawel Jastrzebski, Lukasz Paukszto, Karol Gustaw Makowczenko, Elzbieta Lopienska-Biernat, Marek Gowkielewicz, Ewa Lepiarczyk, Marta Wiszpolska, Mariusz Krzysztof Majewski, Marta Majewska   +9 more
openaire   +4 more sources

Diagnosis, Prevention, and Management of Fetal Growth Restriction (FGR)

Journal of Personalized Medicine
Fetal growth restriction (FGR), or intrauterine growth restriction (IUGR), is still the second most common cause of perinatal mortality. The factors that contribute to fetal growth restriction can be categorized into three distinct groups: placental, fetal, and maternal.
Panagiotis Tsikouras, Panos Antsaklis, Konstantinos Nikolettos, Sonia Kotanidou, Nektaria Kritsotaki, Anastasia Bothou, Sotiris Andreou, Theopi Nalmpanti, Kyriaki Chalkia, Vlasis Spanakis, George Iatrakis, Nikolaos Nikolettos   +11 more
openaire   +3 more sources

FGR: Frustum-Aware Geometric Reasoning for Weakly Supervised 3D Vehicle Detection [PDF]

IEEE International Conference on Robotics and Automation, 2021
In this paper, we investigate the problem of weakly supervised 3D vehicle detection. Conventional methods for 3D object detection usually require vast amounts of manually labelled 3D data as supervision signals.
Yi Wei, Shang-Chin Su, Jiwen Lu, Jie Zhou   +3 more
semanticscholar   +1 more source

An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway

Journal of Translational Medicine, 2023
Background Sepsis-associated encephalopathy (SAE) is characterized by diffuse brain dysfunction, long-term cognitive impairment, and increased morbidity and mortality.
Yuqiang Liu, Han Yang, Nanbo Luo, Yifei Fu, Fang Qiu, Zhenglong Pan, Xiongjuan Li, Wenling Jian, Xinping Yang, Q. Xue, Yan Luo, Buwei Yu, Zhihen Liu   +12 more
semanticscholar   +1 more source

Role of umbilicocerebral and cerebroplacental ratios in prediction of perinatal outcome in FGR pregnancies

Archives of Gynecology and Obstetrics, 2021
Aim of our study was to compare the prognostic value of the Umbilical-to-Cerebral ratio (UCR) directly to the Cerebroplacental ratio (CPR) in the prediction of poor perinatal outcomes in pregnancies complicated by Fetal Growth Restriction (FGR).
H. Coenen, J. Braun, H. Köster, M. Möllers, R. Schmitz, J. Steinhard, K. Oelmeier   +6 more
semanticscholar   +1 more source

DNA Methylation and gene expression patterns are widely altered in fetal growth restriction and associated with FGR development

Animal Cells and Systems, 2021
Fetal growth restriction (FGR) is the failure of the fetus toachieve its genetically determined growth potential, which increasesrisks for a variety of genetic diseases, such as type 2 diabetes mellitus, coronary artery disease, and stroke, during the ...
Seo-Yeon Lee, Young Nam Kim, D. Im, S. Cho, Jiyeon Kim, J. Kim, Kwoneel Kim   +6 more
semanticscholar   +1 more source

Maternal Antioxidant Status in Early Pregnancy and Development of Fetal Complications in Twin Pregnancies: A Pilot Study

Antioxidants, 2020
Twin pregnancies are increasing due to the rise in mothers’ childbearing age and have a higher risk of fetal growth restriction (FGR) and prematurity. Therefore, early prediction of these events is important.
David Ramiro-Cortijo, María de la Calle, Pilar Rodríguez-Rodríguez, Ángel L. López de Pablo, María R. López-Giménez, Yolanda Aguilera, María A. Martín-Cabrejas, María del Carmen González, Silvia M. Arribas   +8 more
doaj   +1 more source

Clinical significance of assessing autoantibody level in diagnostics of early and late fetal growth retardation

Акушерство, гинекология и репродукция, 2022
Aim: to analyze diagnostic potential of early and late fetal growth retardation (FGR) based on examining significance of serum autoimmune antibody (АВ) level.Materials and Methods. A single center prospective cohort comparative study included 98 pregnant
I. V. Ignatko, D. I. Yakubova, A. D. Megrabyan, E. V. Timokhina   +3 more
doaj   +1 more source

Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency

Cell Death and Disease, 2020
Fetal growth restriction (FGR) is the most common pregnancy complication in developed countries. Pregnancies affected by FGR, frequently concur with complications and high risk of neonatal morbidity and mortality.
N. Freitag, I. Tirado-González, G. Barrientos, Katie L. Powell, Philipp Boehm-Sturm, S. Koch, K. Hecher, A. Staff, P. Arck, A. Diemert, S. Blois   +10 more
semanticscholar   +1 more source