Results 61 to 70 of about 54,797 (285)

Gene amplifications associated with the development of hormone- resistant prostate cancer [PDF]

, 2003
Purpose: Hormone resistance remains a significant clinical problem in prostate cancer with few therapeutic options. Research into mechanisms of hormone resistance is essential.
Bartlett, J.M.S., Edwards, J., Krishnan, S., Witton, C.J.   +3 more
core  

Sensitivity to perturbations in a quantum chaotic billiard

, 2002
The Loschmidt echo (LE) measures the ability of a system to return to the initial state after a forward quantum evolution followed by a backward perturbed one.
A. Peres, A. Szafer, A.G. Huibers, Ch. Dellago, D. Cohen, D.A. Wisniacki, Diego A. Wisniacki, E. Vergini, Eduardo G. Vergini, F.M. Cucchietti, F.M. Cucchietti, Fernando M. Cucchietti, G. Benettin, H.M. Pastawski, H.M. Pastawski, Horacio M. Pastawski, L.A. Bunimovich, M. Switkes, N.R. Cerruti, P.G. Silvestrov, Ph. Jacquod, Ph. Jacquod, R. Jalabert   +22 more
core   +1 more source

Energy relaxation rate and its mesoscopic fluctuations in quantum dots [PDF]

, 2016
We analyze the applicability of the Fermi-golden-rule description of quasiparticle relaxation in a closed diffusive quantum dot with electron-electron interaction.
Kozii, Vladyslav A., Skvortsov, Mikhail A.   +1 more
core   +2 more sources

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR

Molecular Medicine Reports, 2018
Fetal growth restriction (FGR) is a gynecological disorder of varying etiology. In the present study, an expression analysis of pregnancy-associated plasma protein A (PAPPA), pregnancy-associated plasma protein A2 (PAPPA2) and placenta-specific-1 (PLAC-1)
S. Sifakis, V. Androutsopoulos, A. Pontikaki, A. Velegrakis, G. Papaioannou, O. Koukoura, D. Spandidos, N. Papantoniou   +7 more
semanticscholar   +1 more source

Alterations in the Gut Microbiome and Metabolisms in Pregnancies with Fetal Growth Restriction

Microbiology Spectrum, 2023
Fetuses diagnosed with fetal growth restriction (FGR) are at an elevated risk of stillbirth and adulthood morbidity. Gut dysbiosis has emerged as one of the impacts of placental insufficiency, which is the main cause of FGR.
Zixin Tao, Yun Chen, Fang He, Jiawei Tang, Limei Zhan, Haoyue Hu, Ziling Ding, Shenghang Ruan, Yutao Chen, Beier Chen, Yan Wang, Xiaoling Guo, Liwei Xie, Mei Zhong, Qitao Huang   +14 more
doaj   +1 more source

Fidelity Decay as an Efficient Indicator of Quantum Chaos

, 2002
Recent work has connected the type of fidelity decay in perturbed quantum models to the presence of chaos in the associated classical models. We demonstrate that a system's rate of fidelity decay under repeated perturbations may be measured efficiently ...
C. Zalka, D. G. Cory, F. Haake, F. Haake, F. Haake, Joseph Emerson, K. Zyczkowski, M. Kus, M. V. Berry, S. Lloyd, Seth Lloyd, Y. S. Weinstein, Yaakov S. Weinstein   +12 more
core   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

The Src family kinase Fgr is a transforming oncoprotein that functions independently of SH3-SH2 domain regulation

Science Signaling, 2018
Sequence differences in the Src family kinase Fgr decrease its autoinhibitory regulation and increase its sensitivity to a myeloproliferative cytokine. Fgr: The maverick in the Src family Members of the family of kinases that includes Src, Hck, Lyn, and ...
Kexin Shen, Jamie A. Moroco, Ravi K. Patel, Haibin Shi, J. Engen, Heather R Dorman, T. Smithgall   +6 more
semanticscholar   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source