Results 71 to 80 of about 1,726,170 (370)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Development of Optical Fiber-Based Daylighting System and Its Comparison
Energies, 2015 Fiber-optic daylighting systems have been shown to be a promising and effective way to transmit sunlight in the interior space whilst reducing electric lighting energy consumption.
Irfan Ullah, Allen Jong-Woei Whang
doaj +1 more source
About the torsion tensor of an affine connection on two-dimensional and three-dimensional manifolds
Дифференциальная геометрия многообразий фигур, 2021 The basis for this study of affine connections in linear frame bundle over a smooth manifold is the structure equations of the bundle. An affine connection is given in this bundle by the Laptev — Lumiste method. The differential equations are written for
K.V. Polyakova
doaj +1 more source
Dynamic critical behavior of failure and plastic deformation in the random fiber bundle model
, 2002 The random fiber bundle (RFB) model, with the strength of the fibers distributed uniformly within a finite interval, is studied under the assumption of global load sharing among all unbroken fibers of the bundle. At any fixed value of the applied stress (
A. Hansen +14 more
core +1 more source
Manuscripta Mathematica, 1992 The author proves that a surjective submersion \(\pi: M\to B\) from a pseudo-Riemannian manifold \(M\) is a fibre bundle, if its fibres are connected totally geodesic and geodesically complete submanifolds of \(M\). This theorem is ``dual'' to R. Hermann's result (1960) about Riemannian submersions and based on the observation that if the surjective ...
openaire +3 more sources
Fiber-bundle-basis sparse reconstruction for high resolution wide-field microendoscopy.
Biomedical Optics Express, 2018 In order to observe deep regions of the brain, we propose the use of a fiber bundle for microendoscopy. Fiber bundles allow for the excitation and collection of fluorescence as well as wide field imaging while remaining largely impervious to image ...
S. Mekhail +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Cartan Connections and Atiyah Lie Algebroids [PDF]
, 2019 This work extends previous developments carried out by some of the authors on Ehresmann connections on Atiyah Lie algebroids. In this paper, we study Cartan connections in a framework relying on two Atiyah Lie algebroids based on a $H$-principal fiber ...
Attard, Jeremy +3 more
core +1 more source
Principal Co-Fiber Bundles [PDF]
Transactions of the American Mathematical Society, 1976 Principal co-fiber bundles are defined in the category of topological groups. They are Eckmann-Hilton duals of principal fiber bundles. A classification theorem is provided as well as an example which almost represents the most general case.
openaire +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source