Results 41 to 50 of about 2,014,083 (293)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Switchable dual-wavelength Q-switched fiber laser based on sputtered indium tin oxide as saturable absorber

open access: yesResults in Physics, 2020
This paper demonstrate experimentally the generation of a stable switchable dual-wavelength Q-switched fiber laser. The pulsed fiber lasers is generated from deposited Indium Tin Oxide (ITO) saturable absorber (SA) on fiber ferrule, which is prepared by ...
N.U.H.H. Zalkepali   +5 more
doaj   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth   +6 more
wiley   +1 more source

Self‐Powered Stretchable Mechanoluminescent Optical Fiber Strain Sensor

open access: yesAdvanced Intelligent Systems, 2021
Strain sensors that can work sustainably and continuously without any external power supply are highly desirable for future wearable and implantable devices.
Haohua Liang   +10 more
doaj   +1 more source

Fabrication of Microchannels in a Nodeless Antiresonant Hollow-Core Fiber Using Femtosecond Laser Pulses

open access: yesSensors, 2021
In this work, we present femtosecond laser cutting of microchannels in a nodeless antiresonant hollow-core fiber (ARHCF). Due to its ability to guide light in an air core combined with exceptional light-guiding properties, an ARHCF with a relatively non ...
Paweł Kozioł   +9 more
doaj   +1 more source

321W average power, 1GHz, 20ps 1060nm pulsed fiber MOPA source [PDF]

open access: yes, 2005
Pulses from a gain-switched laser diode were amplified in a fiber MOPA system to produce in excess of 320W of average power in 20ps pulses at 1GHz repetition rate at ...
Jeong, Y.   +9 more
core   +2 more sources

Investigating the Effect of Inclination Angle and the Influence of Scan Parameters on the Appearance and Thermal and Mechanical Properties of Filigree Tension Rods of LPBF‐Manufactured NiTi Shape‐Memory Alloys

open access: yesAdvanced Engineering Materials, EarlyView.
This article investigates the dependence of the properties on the manufacturing orientation in the form of the inclination angle to the build plate of LPBF‐fabricated NiTi rods with a diameter of 150–220 µm. Metallographic, chemical, thermal, and mechanical characterization show behavior under identical manufacturing conditions that ranges from ...
Sandra Herzig   +2 more
wiley   +1 more source

Supercontinuum Generation in an Ytterbium-Doped Fiber Amplifier With Cascaded Double-Clad Passive Fiber Tapers

open access: yesIEEE Photonics Journal, 2017
Supercontinuum (SC) generation directly from an Ytterbium-doped fiber amplifier (YDFA) has many advantages such as high output power, low splicing loss, and high optical to optical conversion efficiency.
Chengmin Lei   +4 more
doaj   +1 more source

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